Nerve pain

💊 Behandelingen bij nerve pain

Gerangschikt op onderbouwing (aantal onafhankelijke bronnen) en gerapporteerde frequentie.

+ Enkel op voorschrift — bespreek met je arts

• +Pregabalin6 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Pregabalin is a gamma-aminobutyric acid analog that binds to the α2δ-subunit of voltage-dependent calcium channels in the central nervous system, thereby reducing calcium influx and the release of excitatory neurotransmitters.

  Dosage: 150 to 600 mg per day, divided into two or three doses.
• +Duloxetine5 bronnenop voorschrift — vraag je arts
  About the substance

  Duloxetine is a combined serotonin (5-HT) and norepinephrine (NA) reuptake inhibitor. By increasing extracellular levels of these neurotransmitters in the central nervous system, it normalizes pain thresholds and influences mood.

  Dosage: 60 mg once daily, to be taken with or without food.
• +Capsaicin4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Highly selective agonist for the TRPV1 receptor (transient receptor potential vanilloid 1). The mechanism relies on initial activation of nociceptors followed by desensitization, making them less sensitive to stimuli.

  Dosage: Apply a maximum of 4 patches to intact, dry skin by a healthcare professional; application time 30 minutes for the feet and 60 minutes for other body parts.
• +Gabapentin3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Gabapentin is an antiepileptic drug that binds to the α2δ subunit of voltage-gated calcium channels in the central nervous system, thereby modulating neurotransmission.

  Dosage: Starting schedule for adults/adolescents (≥12 years): day 1: 300 mg once daily, day 2: 300 mg twice daily, day 3: 300 mg three times daily. Discontinue by gradually tapering over at least 1 week.
• +Amitriptyline Hydrochloride2 bronnenop voorschrift — vraag je arts
  About the substance

  Tricyclic antidepressant that inhibits the reuptake of norepinephrine and serotonin, and also possesses ion channel blocking effects (sodium, potassium, NMDA) and anticholinergic properties.

  Dosage: Adults (depression): starting dose 25 mg twice daily, gradually increased to a maximum of 150 mg per day.
• +Nortriptyline2 bronnenop voorschrift — vraag je arts
  About the substance

  Tricyclic antidepressant (TCA) with thymoanaleptic and psychostimulant properties. It works primarily by inhibiting the reuptake of neurotransmitters in the synaptic cleft, which improves mood.

  Dosage: Starting dose 50 mg/day (or 25 mg 2-3 times daily), gradually increase. Doses above 150 mg/day preferably in a clinical setting (max. 200-250 mg/day).
• +Clonidine2 bronnenop voorschrift — vraag je arts
  About the substance

  Clonidine is an imidazole derivative and centrally acting alpha-2-adrenergic agonist. By stimulating alpha-2 receptors in the medulla oblongata, sympathetic outflow is inhibited, leading to a reduction in peripheral resistance and heart rate.

  Dosage: Starting dose for hypertension: 75-150 micrograms twice daily. The dose can be increased in steps up to a maximum of 600 micrograms daily.

Bron: dis-treat master (BCFI/itreat · EMA · SIDER · FAERS-frequentie). Geen diagnose — dit vervangt geen consult.