Constipation

💊 Behandelingen bij constipation

Gerangschikt op onderbouwing (aantal onafhankelijke bronnen) en gerapporteerde frequentie.

+ Vrij verkrijgbaar bij ons

• +Bisacodyl11 bronnen🟢Bisacodyl Eg 5mg Omhulde Tabl 40 X 5mg€ 6,10
  About the substance

  Bisacodyl is a contact laxative from the diphenylmethane derivative group that stimulates peristalsis and promotes the accumulation of water and electrolytes in the intestinal lumen.

  Dosage: Adults and children aged 10-11 years and older: 5-10 mg (1-2 tablets) daily before bedtime, or 1 suppository (10 mg) for immediate effect.
• +Lactulose12 bronnen🟠Lactulose Eg Sirop 300ml€ 7,87🟠Lactulose Teva Sol Per Os 500 Ml€ 9,42🟠Lactulose Eg Sirop 500ml€ 11,26Meer uit 7 →
  About the substance

  Osmotic laxative that is converted into organic acids by intestinal flora in the colon, leading to a pH drop and osmotic volume increase of the intestinal contents, resulting in stimulation of peristalsis.

  Dosage: Individually determined; for constipation usually once daily (e.g., during breakfast), for liver diseases 3-4 times daily. Adjust dosage based on response after 2-3 days.
• +Macrogol5 bronnen🟠Macrogol + Electr Sandoz Pdr Ciroensmaak Zakje 8€ 5,10🟠Macrogol Ab 4g Pdr Voor Drank Zakje 20€ 8,59🟠Forlax Junior 4 G Sachets - Zakjes 20€ 9,90Meer uit 40 →
  About the substance

  Osmotic laxative; macrogols are long polymers that retain water in the intestine via hydrogen bonds, increasing fluid volume and softening the stool.

  Dosage: Adults and elderly: 2 sachets per day, preferably taken in the morning after dissolving in 100 ml of water.
• +Sorbitol6 bronnen🟢Mvw Complete Formul. Multivit. Sinaas Kauwtabl 60€ 52,30
  About the substance

  A polyhydric alcohol that acts as an osmotic laxative by drawing water into the bowel, which accelerates intestinal transit.
• +Glycerin5 bronnen🟠Phlexy-vits Tabl 60x1,7g€ 49,03🟠Gte Olie 1l€ 1.069,68
  About the substance

  Osmotic laxative that draws water into the bowel and mildly stimulates the intestinal mucosa, leading to accelerated bowel transit.

  Dosage: Adults: 1 to 2 suppositories per day; children < 6 years: 1-1.7 grams rectally; administer as needed.
• +Picosulfate sodium3 bronnen🟠Dulcolax Picosulphate Caps 50x2,5mg€ 11,14🟠Citrafleet Poeder Drank 2 Zakjes€ 18,92🟠Picoprep Poeder Voor Drank 1 X 2 Zakjes€ 20,12
  About the substance

  Contact laxative from the diphenylmethane derivative group; it is hydrolyzed by intestinal flora into an active metabolite that stimulates intestinal peristalsis and inhibits the reabsorption of water and electrolytes.

  Dosage: Adults and children from 10 years: 10-20 drops (5-10 mg) per day. Children 4-10 years: 5-10 drops (2.5-5 mg) per day. Children under 4 years: 0.25 mg per kg of body weight per day. All dosages in one daily intake.
• +Methylcellulose3 bronnen🟠Phlexy-vits Tabl 60x1,7g€ 49,03
  About the substance

  A hydrophilic polymer that acts as a bulk-forming laxative by absorbing water and forming a gel, thereby promoting intestinal passage.
• +Guar gum2 bronnen🟠Spagulax Efferv Sach 20 X 5 G€ 8,34

+ Enkel op voorschrift — bespreek met je arts

• +Mineral Oil7 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Laxative with a lubricating effect that softens stool and accelerates intestinal transit by forming a physical barrier and lubricant in the intestinal lumen.

  Dosage: Adults and children >15 years: 1-3 tablespoons per day. Children 4-15 years: 1-3 teaspoons per day. Preferably taken in the morning on an empty stomach or 2 hours before/after the main meal.
• +Magnesium citrate6 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  This is an osmotic laxative. It draws water from the surrounding tissue into the intestinal lumen. Due to the increased amount of fluid in the intestine, the stool becomes softer and its volume increases, which stimulates bowel movements.

  Dosage: Use according to the packaging, usually 150-300 ml of solution; do not use long-term without medical advice.
• +Castor oil7 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  In the intestine, ricinoleic acid is released from the oil. This acid slightly irritates the intestinal wall and directly stimulates intestinal peristalsis, while also inhibiting the absorption of water and electrolytes in the intestine. This leads to a rapid and powerful emptying of the bowels.

  Dosage: Not suitable for self-care without medical supervision due to its powerful effect.
• +Lubiprostone6 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Lubiprostone is a prostaglandin E1 derivative that activates ClC-2 chloride channels on the apical side of gastrointestinal epithelial cells. This promotes the secretion of chloride-rich fluid, which softens the stool and increases intestinal motility.

  Dosage: 1 capsule twice daily, to be taken in the morning and evening with food; swallow whole.
• +Magnesium Hydroxide8 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  As an antacid, it directly neutralizes existing stomach acid through a chemical reaction. As a laxative, it works osmotically by retaining water in the intestine, which softens the stool and promotes bowel transit.

  Dosage: Follow the instructions on the packaging; do not use for longer than 14 consecutive days.
• +Linaclotide5 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Guanylate cyclase-C (GC-C) receptor agonist. By binding to the GC-C receptor on the intestinal epithelium, it increases the secretion of fluid and electrolytes into the intestinal lumen and reduces visceral pain sensitivity.

  Dosage: 1 capsule of 290 micrograms once daily, take at least 30 minutes before a meal.
• +Docusate Sodium4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Emollient laxative that lowers the surface tension of feces, allowing water to better penetrate the stool and soften it.
• +Methylnaltrexone5 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  It is a peripheral opioid receptor antagonist. It blocks the action of opioids specifically in the intestines, without affecting the pain-relieving effect in the brain. This restores intestinal movement that was slowed down by the painkillers.
• +Magnesium oxide5 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  As an antacid, it reacts with stomach acid to lower the acidity in the stomach. As a supplement, it helps replenish a magnesium deficiency, which is essential for muscle and nerve functions. It is slowly converted in the intestine into absorbable magnesium ions.

  Dosage: Follow the dosage on the packaging; do not use for longer than 14 days for stomach complaints.
• +Sennosides, USP4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  These are contact laxatives that are converted into active substances in the large intestine. These substances stimulate the nerve plexus in the intestinal wall, leading to increased bowel peristalsis. This causes stool to be transported through the intestine more quickly.

  Dosage: Use the lowest possible dose for a short period; do not use for longer than 1 week.
• +Docusate4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Docusate is a surfactant that lowers the surface tension of the stool. This allows water and fats to penetrate the stool more easily. This makes the stool softer and facilitates passage through the intestine.

  Dosage: Use according to the packaging; do not combine with mineral oils.
• +Naldemedine3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Peripherally acting mu-opioid receptor antagonist; it blocks the constipating effects of opioids in the gastrointestinal tract without affecting central pain relief due to limited passage across the blood-brain barrier.

  Dosage: 1 tablet of 200 micrograms once daily, to be taken at a fixed time, with or without food.
• +Tegaserod4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tegaserod is a selective 5-HT4 receptor agonist that promotes intestinal motility by acting on serotonin-4 receptors in the smooth muscle cells of the gastrointestinal tract, leading to increased peristalsis and secretion.

  Dosage: 1 tablet twice daily, to be taken on an empty stomach shortly before a meal.
• +POLYETHYLENE GLYCOL 33504 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  This is an osmotic laxative that is not absorbed by the body. It binds to water in the intestine, keeping the stool hydrated and increasing its volume. This provides natural stimulation of bowel movement without irritating the intestinal wall.

  Dosage: Dissolve 1 to 2 sachets per day in water; always drink sufficient fluids.
• +Naloxegol3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Peripherally selective opioid antagonist; a PEGylated form of naloxol that, due to its structure, does not cross the blood-brain barrier and specifically blocks peripheral opioid receptors in the gastrointestinal tract.

  Dosage: Standard 25 mg once daily, to be taken in the morning on an empty stomach (at least 30 minutes before or 2 hours after breakfast). For severe gastrointestinal side effects or moderate to severe renal impairment: 12.5 mg once daily.
• +Sodium phosphate, monobasic3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Sodium phosphate is an osmotic laxative. It draws water from the surrounding tissue into the intestinal lumen through osmosis. This softens the stool and increases its volume, which stimulates bowel movements and facilitates defecation.

  Dosage: Follow the instructions on the packaging carefully; do not exceed the maximum daily dosage to prevent disruption of the electrolyte balance.
• +Sodium phosphate3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  This is an inorganic salt that serves as a source of phosphate and sodium ions. Phosphate is essential for cellular energy metabolism (ATP synthesis) and the acid-base balance in the blood. Through direct administration, the deficiency in the extracellular compartment is replenished.
• +Magnesium sulfate4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Magnesium sulfate acts as an osmotic laxative that accelerates bowel transit. In diagnostic use, it ensures rapid emptying of the bowels, making the mucosa more visible during imaging. It increases fluid retention in the intestine, which cleanses the intestinal wall.
• +Psyllium3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Psyllium consists of natural fibers that absorb large amounts of water. This causes the stool to swell in the intestine, which provides a larger volume and a softer consistency. This stimulates natural bowel movement in a mechanical way.

  Dosage: Take 1 sachet or 1-2 teaspoons 1 to 3 times daily with a large glass of water; always drink plenty of fluids.
• +Suppository2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A suppository consists of a fat- or water-soluble base that melts or dissolves at body temperature. This releases the active substance, which is then absorbed directly through the mucous membrane of the rectum into the bloodstream. This partially bypasses the first-pass metabolism in the liver, which can increase bioavailability.

  Dosage: Insert the suppository deep into the anus; the dosage depends on the active substance in the suppository.
• +Prucalopride2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Prucalopride is a selective 5-HT4 receptor agonist that stimulates propulsive gastrointestinal motility by binding to serotonin receptors in the intestinal wall.

  Dosage: Adults: 2 mg once daily. Elderly (>65 years) and patients with severe hepatic impairment: start with 1 mg once daily, increase to 2 mg if necessary. Can be taken at any time of the day, with or without food.
• +Cascara sagrada2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Cascara is a natural laxative (stimulant laxative) that increases intestinal motility by stimulating the peristalsis of the large intestine.

  Dosage: 20-30 mg of hydroxyanthracene derivatives per day; liquid extract: 2-5 ml 3 times daily; tea: 2 grams of bark in 150 ml of boiling water.
• +Plecanatide2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Guanylate cyclase-C (GC-C) agonist that stimulates the secretion of chloride and bicarbonate into the intestinal lumen, leading to increased fluid retention and accelerated bowel transit.
• +Lactitol2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Lactitol is an osmotic laxative (sugar alcohol) that retains water in the intestine and influences intestinal flora by acidifying the intestinal contents.

  Dosage: Adults: starting dose 20 g once daily. Children: 0.25 g/kg body weight per day. Adjust dosage individually based on the desired bowel movement frequency.
• +Ispaghula husk2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ispaghula (psyllium husk) belongs to the group of bulk-forming laxatives. The fibers absorb large amounts of water in the intestine, causing them to swell and form a gel-like mass. This increases the volume of the stool and makes it softer, which naturally stimulates the intestinal wall to contract.

  Dosage: Take with a large glass of water (at least 200 ml) to prevent esophageal obstruction; maximum 3 times per day.
• +Calcium polycarbophil2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A synthetic polymer and stool stabilizer that regulates stool consistency through an exceptionally high water-binding capacity.
• +Phenolphthalein2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A contact laxative that stimulates intestinal motility by promoting the secretion of water and electrolytes into the intestinal lumen.
• +Others2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  The mechanism varies by specific product, but these agents are generally designed to support the skin's barrier function or reduce irritation. They often work by applying a protective layer to the skin or by regulating the moisture content in the stratum corneum.

Bron: dis-treat master (BCFI/itreat · EMA · SIDER · FAERS-frequentie). Geen diagnose — dit vervangt geen consult.