Spasms

💊 Behandelingen bij spasms

Gerangschikt op onderbouwing (aantal onafhankelijke bronnen) en gerapporteerde frequentie.

+ Enkel op voorschrift — bespreek met je arts

• +Cyclobenzaprine7 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant with a structure related to tricyclic antidepressants; it works by influencing motor activity in the brainstem.

  Dosage: Tablets: 2-4 times daily; extended-release capsules: 1-2 times daily. Maximum duration of use: 3 weeks.
• +Tizanidine4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant and alpha-2 adrenergic receptor agonist. It inhibits polysynaptic signal transmission in the spinal cord through presynaptic stimulation of alpha-2 receptors, thereby reducing the release of excitatory amino acids.

  Dosage: Starting dose 2 mg 3 times daily. The dosage should be titrated individually. In case of renal or hepatic insufficiency, the maximum initial daily dose is 6 mg, divided into 3 doses.
• +Guaiphenesin carbamate3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant of the guaiacol glyceryl ether class; the mechanism is based on general suppression of the central nervous system, leading to muscle relaxation and pain relief.

  Dosage: Up to 1500 mg four times daily for 2-3 days; 3 to 6 times per day is common.
• +Tolperisone Hydrochloride3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant that blocks sodium and calcium channels in the central nervous system, particularly in the brainstem and spinal cord.
• +Baclofen4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Baclofen is a GABA-β receptor agonist that acts as a centrally acting spasmolytic. By stimulating these receptors in the spinal cord, it suppresses mono- and polysynaptic reflex transmission, leading to muscle relaxation.

  Dosage: The dosage is strictly individual and requires titration; for intrathecal administration, a test phase via bolus injection is started, followed by continuous infusion via an implantable pump.
• +Carisoprodol3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant that suppresses neuronal communication in the reticular formation and the spinal cord.

  Dosage: Three times daily and at bedtime.
• +THIOCOLCHICOSIDE2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  This is a muscle relaxant that acts on GABA-A receptors and glycine receptors in the central nervous system. By activating these receptors, it reduces muscle tension and excessive reflex activity. This helps to relieve painful cramping.
• +Hyoscyamine3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A tropane alkaloid and antimuscarinic substance that acts as a competitive antagonist of acetylcholine at muscarinic receptors.

  Dosage: Tablets/liquid: 3-4 times per day. Extended-release capsules: 2 times per day (do not chew or crush). Antacids should be used 1 hour before or 2 hours after intake.
• +Aspirin / caffeine / orphenadrine2 bronnenniet vrij verkrijgbaar — vraag je arts
• +Chlorzoxazone2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant that inhibits muscle spasms by acting on the spinal cord and subcortical brain areas.

  Dosage: Take orally 3 to 4 times daily.
• +Butylscopolamine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Peripherally acting antimuscarinic and anticholinergic agent (quaternary ammonium compound) that relieves spasms in smooth muscle cells of the gastrointestinal, biliary, and urinary systems by blocking parasympathetic ganglia and muscarinic receptors.

  Dosage: Adults and children >12 years: 20-40 mg per dose, maximum 100 mg per day, parenterally (IV, IM, or SC). Children: 0.3-0.6 mg/kg per dose, maximum 1.5 mg/kg per day, parenterally.
• +Dicyclomine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Dicycloverine is a muscarinic receptor antagonist (M1, M2, M3) and non-competitive inhibitor of histamine and bradykinin that relaxes the smooth muscles in the gastrointestinal tract.

  Dosage: Usually 4 times per day; the doctor typically starts with a low dose that is gradually increased.
• +Cisatracurium2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  It is a non-depolarizing neuromuscular blocking agent. It blocks acetylcholine receptors at the motor endplate of the muscle, preventing nerve impulses from reaching the muscle. This results in complete relaxation of striated muscles.
• +Dantrolene2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Direct-acting skeletal muscle relaxant that binds to the ryanodine receptor-1 (RYR1) and suppresses calcium release from the sarcoplasmic reticulum.

  Dosage: Intravenous: initial dose of 2.5 mg/kg, repeat every 10 minutes until symptoms improve.
• +Papaverine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A directly acting, non-specific antispasmodic for smooth muscle; it likely works via phosphodiesterase inhibition and direct influence on calcium channels.

  Dosage: Adults: 30-120 mg via subcutaneous, intramuscular, or intravenous injection, repeat every 3 hours if necessary. Pediatric: 1.5 mg/kg 4 times per day (intravenous administration is discouraged under 15 years of age).
• +Orphenadrine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  This agent acts as a centrally acting muscle relaxant with anticholinergic properties. It blocks the action of acetylcholine in the central nervous system, which reduces muscle tension. Additionally, it has a mild analgesic effect due to its influence on pain perception in the brain.

Bron: dis-treat master (BCFI/itreat · EMA · SIDER · FAERS-frequentie). Geen diagnose — dit vervangt geen consult.