Joint pain

💊 Behandelingen bij joint pain

Gerangschikt op onderbouwing (aantal onafhankelijke bronnen) en gerapporteerde frequentie.

+ Vrij verkrijgbaar bij ons

• +Succinic Acid1 bron🟠Dekas Essential Caps 60€ 52,30
  About the substance

  Succinic acid is a natural intermediate in the citric acid cycle, the process by which cells produce energy from nutrients. By increasing the supply of this acid, mitochondrial respiration is supported. This helps to optimize cellular energy production and metabolism.
• +Auranofin1 bron🟠Mvw Complete Formul. Multivitamin D3000 Softgel 60€ 52,30
  About the substance

  Auranofin is an oral gold salt and anti-rheumatic drug that suppresses inflammation by inducing heme oxygenase-1 (HO-1), an enzyme with anti-inflammatory properties.

  Dosage: Capsule, usually taken 1 to 2 times daily as prescribed.
• +Dexibuprofen1 bron🟠Ibuprofen Ab 200mg Filmomh Tabl 24€ 3,90
  About the substance

  Dexibuprofen is the active S(+)-isomer of ibuprofen. It is an NSAID that inhibits the production of prostaglandins by blocking cyclooxygenase enzymes. Because it is the active form, a lower dosage is required than with the racemic mixture to achieve the same anti-inflammatory and analgesic effect.
• +Magnesium Oxide1 bron🟠Dr Scheffler Vit C Bruistabletten 20x1g€ 4,95
  About the substance

  As an antacid, it reacts with stomach acid to lower the acidity in the stomach. As a supplement, it helps replenish a magnesium deficiency, which is essential for muscle and nerve functions. It is slowly converted in the intestine into absorbable magnesium ions.

  Dosage: Follow the dosage on the packaging; do not use for longer than 14 days for stomach complaints.
• +Cod Liver Oil1 bron🟢Nutramigen 3 Lgg Pdr 400g€ 24,00
  About the substance

  Cod liver oil is rich in omega-3 fatty acids (EPA and DHA) and vitamins A and D. Omega-3 fatty acids are building blocks for cell membranes and have an anti-inflammatory effect on the cardiovascular system, while vitamins A and D are essential for vision and calcium metabolism, respectively.
• +Loperamide1 bron🟢Loperamide Teva Caps 20 X 2 Mg€ 6,94🟢Loperamide Ab 2mg Harde Caps 20 X 2mg€ 7,04🟢Loperamide Eg Caps 20x2mg€ 7,21Meer uit 17 →
  About the substance

  Loperamide is a synthetic phenylpiperidine opioid that acts as a μ-opioid receptor agonist in the intestinal wall. By inhibiting the release of acetylcholine and prostaglandins, it reduces propulsive peristalsis and prolongs intestinal transit time.

  Dosage: Acute diarrhea: starting dose 4 mg, followed by 2 mg after each loose stool (max. 16 mg/day). Chronic diarrhea: adjust dosage until 1-2 formed stools per day are achieved (usually 2-12 mg/day).
• +Magaldrate1 bron🟢Riopan Gel Sachets Zakjes 50x10ml€ 17,90
  About the substance

  Antacid with a layered lattice structure that neutralizes stomach acid, binds pepsin and bile components, and forms a protective layer on the stomach wall.

  Dosage: Adults and children from 12 years: 800 mg per day for mild symptoms; for gastric ulcer 800 mg 1 hour after meals and at bedtime; for duodenal ulcer 800-1600 mg 1 and 3 hours after meals and at bedtime. Maximum daily dose: 6400 mg.
• +Glucosamine1 bron🟢Glucosamine Pharma Nord Caps 90 X 400 Mg€ 13,50🟢Glucosamine Pharma Nord Caps 270 X 400 Mg€ 32,85🟠Dolenio 1178mg Flacon Filmomh Tabl 90€ 30,60Meer uit 4 →
  About the substance

  Glucosamine is a substance produced by the body that forms a building block for glycosaminoglycans in cartilage. Supplementation supports the synthesis of cartilage matrix, which can contribute to the maintenance of joint structure. This process helps to reduce pain and stiffness in affected joints.

  Dosage: Use a maximum of 1500 mg per day; do not exceed the recommended dosage.
• +Ferrous fumarate1 bron🟠Modulen Ibd Pdr Bte 400g 12259922€ 14,29
  About the substance

  Ferrous fumarate is an iron salt that provides the body with elemental iron, an essential mineral for the production of hemoglobin. Hemoglobin is the protein in red blood cells responsible for transporting oxygen throughout the body. By replenishing iron levels, the production of healthy red blood cells is restored and oxygen supply is improved.

  Dosage: Usually 100 to 200 mg of elemental iron per day, preferably on an empty stomach for better absorption.
• +Diphenhydramine Hydrochloride1 bron🟢Nustasium Comp 20€ 14,90
  About the substance

  First-generation H1-receptor antagonist from the ethanolamine series that competitively blocks histamine H1-receptors in both the periphery and the central nervous system.

  Dosage: Apply only small amounts to the irritated skin using a gentle massage; use for a maximum of 7 days without medical advice.
• +Evening primrose oil1 bron🟠Heparon Junior 400g€ 19,02
  About the substance

  The oil is rich in gamma-linolenic acid (GLA), an essential omega-6 fatty acid. GLA is a precursor to prostaglandin E1, a substance that has anti-inflammatory properties and supports cell membrane structure. This helps in repairing the skin barrier and regulating hormonal imbalances.

  Dosage: The usual dosage varies; consult the packaging for the recommended daily intake.
• +Glycerin1 bron🟠Phlexy-vits Tabl 60x1,7g€ 49,03🟠Gte Olie 1l€ 1.069,68
  About the substance

  Osmotic laxative that draws water into the bowel and mildly stimulates the intestinal mucosa, leading to accelerated bowel transit.

  Dosage: Adults: 1 to 2 suppositories per day; children < 6 years: 1-1.7 grams rectally; administer as needed.
• +Naproxen1 bron🟠Aleve Comp 24€ 8,00
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase (COX), leading to reduced synthesis of prostaglandins.

  Dosage: 1 tablet twice daily, preferably taken with water at least 30 minutes before a meal.
• +Lactulose1 bron🟠Lactulose Eg Sirop 300ml€ 7,87🟠Lactulose Teva Sol Per Os 500 Ml€ 9,42🟠Lactulose Eg Sirop 500ml€ 11,26Meer uit 7 →
  About the substance

  Osmotic laxative that is converted into organic acids by intestinal flora in the colon, leading to a pH drop and osmotic volume increase of the intestinal contents, resulting in stimulation of peristalsis.

  Dosage: Individually determined; for constipation usually once daily (e.g., during breakfast), for liver diseases 3-4 times daily. Adjust dosage based on response after 2-3 days.
• +Activated Charcoal1 bron🟢Carbobel Mono 300mg Comp 35€ 9,59🟢Norit 250 Tabl 75€ 10,87🟠Norit Carbomix Fl Gran. 61,5 G€ 17,47
  About the substance

  Intestinal adsorbent that binds harmful substances, gases, and drugs to its surface through a large internal surface area via non-selective adsorption.

  Dosage: Poisoning: 50-100 g (adults), approx. 1 g/kg (children), as soon as possible; Diarrhea: 2.5 to 3.5 g per day in adjusted doses.
• +CIDER VINEGAR1 bron🟠Pku Lophlex Lq 20 Juicy Bosvruchten 30x125ml€ 513,00
  About the substance

  Apple cider vinegar contains acetic acid, which can affect stomach acidity. It is believed to slightly improve insulin sensitivity after a meal and delay glycemic response by inhibiting gastric emptying. This may contribute to a more stable blood sugar level after eating.
• +Acetaminophen1 bron🟠Paracetamol Kruidvat Health 500mg Comp 20€ 1,85
  About the substance

  Analgesic and antipyretic from the anilide group. Its mechanism of action is based on the inhibition of cerebral prostaglandin synthesis and counteracting the effect of endogenous pyrogens on the hypothalamus.

  Dosage: 10 to 15 mg/kg of body weight per dose, with a maximum of 60 mg/kg per day; at least 4 hours between doses.
• +Choline1 bron🟠Easiphen Bosvruchten 250ml€ 13,89
  About the substance

  Choline is an essential nutrient that acts as a precursor for phosphatidylcholine, an important component of cell membranes. It plays a crucial role in transporting fats out of the liver and is involved in the synthesis of acetylcholine, a neurotransmitter for the nervous system. This supports normal liver function and fat metabolism.
• +Colchicine1 bron🟠Colchicine Lirca 1mg Tabl 60€ 20,40
  About the substance

  Colchicine is an alkaloid that inhibits the polymerization of tubulin into microtubules, thereby suppressing cell migration and phagocytosis of neutrophil granulocytes.

  Dosage: Acute gout: 0.5 mg 2-3 times daily (starting dose of 1 mg may be used), maximum 6 mg per course. Prevention/FMF: 1-2 times daily.
• +Pyridoxine1 bron🟠Befact Forte B1-b2-b6-b12 Omhulde Tabl 30€ 10,91
  About the substance

  Pyridoxine is converted in the body into pyridoxal phosphate, a coenzyme involved in more than a hundred enzymatic reactions, particularly in protein metabolism. It plays a crucial role in the synthesis of neurotransmitters such as serotonin and dopamine. This supports the normal functioning of the nervous system and metabolism.

  Dosage: Adhere to the recommended daily dosage; long-term use of high doses can lead to nerve damage.
• +Loratadine1 bron🟠Loratadine Eg 10 Mg Tabl 10 X 10 Mg€ 6,83🟠Loratadine Teva 10 Mg Comp 50 X 10 Mg€ 9,64🟠Loratadine Sandoz Comp 30 X 10 Mg€ 9,76Meer uit 8 →
  About the substance

  Loratadine is a selective, peripherally acting second-generation antihistamine that blocks the H1 receptor. Due to its limited passage across the blood-brain barrier, it exhibits almost no sedative or anticholinergic effects.

  Dosage: Adults and children >30 kg: 1 tablet of 10 mg once daily. Children 2-6 years (≤30 kg): 5 mg once daily. In case of severe liver insufficiency: halve the dosage (every other day).
• +Ethanol1 bron🟠Antistax Forte Filmomh Tabl 60€ 35,58🟠Antistax Forte Pi Pharma 360mg Filmomh Tabl 90 Pip€ 44,53🟠Antistax Forte Filmomhulde Tabl 90€ 44,53
  About the substance

  Ethanol is an alcohol that works by denaturing the proteins in the cell wall and cytoplasm of microorganisms. By destroying these protein structures, the cell loses its integrity and the microorganism dies. This process is highly effective against a broad spectrum of pathogens upon direct contact.
• +Ibuprofen1 bron🟠Ibuprofen Ab 200mg Filmomh Tabl 24€ 3,90🟠Ibuprofen Sandoz 200mg Filmomh Tabl 30€ 4,95🟠Nurofen Kind 200mg Filmomh Tabl 24 Verv.2475739€ 5,14Meer uit 42 →
  About the substance

  Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that acts as a non-selective inhibitor of the cyclooxygenase enzyme, leading to reduced synthesis of prostaglandins.

  Dosage: For patent ductus arteriosus: 3 intravenous injections at 24-hour intervals (1st dose 10 mg/kg, 2nd and 3rd dose 5 mg/kg). For pain/fever in adults and children >12 years: every 4-6 hours if needed.
• +Magnesium Hydroxide1 bron🟠Dr Scheffler Vit C Bruistabletten 20x1g€ 4,95🟠Maalox Antacid 230mg/400mg/10ml Susp Oraal 250ml€ 10,29🟠Novalac Aminova 0-36m Pdr 400g€ 42,30Meer uit 4 →
  About the substance

  As an antacid, it directly neutralizes existing stomach acid through a chemical reaction. As a laxative, it works osmotically by retaining water in the intestine, which softens the stool and promotes bowel transit.

  Dosage: Follow the instructions on the packaging; do not use for longer than 14 consecutive days.
• +Guaifenesin1 bron🟠Vicks Slijmhoest Siroop 180ml€ 10,40🟠Bronchosedal Mucus Menthol 150ml 20mg/ml€ 10,48🟠Toularynx Guaifenesine 13,33mg/ml Siroop 180ml€ 11,72Meer uit 4 →
  About the substance

  Guaifenesin is an expectorant that stimulates the gastric mucosa, which via a reflex leads to increased secretion by the glands in the gastrointestinal tract and respiratory tract, resulting in an increase in volume and a decrease in the viscosity of bronchial secretions.

  Dosage: Adults and adolescents (≥12 years): 200 mg 4 times daily (max. 800 mg/day). Children (6-12 years): 100 mg 4 times daily (max. 400 mg/day).
• +Potassium Iodide1 bron🟠Easiphen Bosvruchten 250ml€ 13,89
  About the substance

  Potassium iodide saturates the thyroid gland with stable iodine. When the thyroid is saturated, it can no longer absorb radioactive iodine from the bloodstream. This prevents radioactive particles from accumulating in the thyroid and causing damage or cancer there.
• +Omeprazole1 bron🟠Acidcare 20 Mg Sandoz Caps Maagsapres 14 X 20 Mg€ 14,51🟠Acidcare 10 Mg Sandoz Caps Maagsapres 28 X 10 Mg€ 14,66
  About the substance

  Proton pump inhibitor (PPI) that inhibits gastric acid secretion by reversible blockade of the H+/K+-ATPase enzyme in the parietal cells of the stomach.

  Dosage: 20 mg once daily; if response is insufficient, 40 mg once daily; take at least 1 hour before a meal.
• +Vitamin B61 bron🟠Befact Forte B1-b2-b6-b12 Omhulde Tabl 30€ 10,91
  About the substance

  Vitamin B6 acts as an essential cofactor for more than a hundred enzymatic reactions in the body, particularly in protein metabolism. It is involved in the synthesis of neurotransmitters such as serotonin and dopamine. Through this enzymatic support, it helps regulate energy balance and neurological functions.

  Dosage: The recommended daily amount for adults is usually 1.5 mg; do not exceed the safe upper limit of 25 mg per day.
• +Magnesium Sulfate1 bron🟠Dr Scheffler Vit C Bruistabletten 20x1g€ 4,95
  About the substance

  Magnesium sulfate acts as an osmotic laxative that accelerates bowel transit. In diagnostic use, it ensures rapid emptying of the bowels, making the mucosa more visible during imaging. It increases fluid retention in the intestine, which cleanses the intestinal wall.
• +Sodium Bicarbonate1 bron🟠Movigo Duo Kant-en-klare Drank Zakjes 10
  About the substance

  Systemic alkalizer and pH buffer that lowers the hydrogen ion concentration in body fluids through the neutralization of acids.

  Dosage: Athletic performance: 100-400 mg/kg body weight, 1-3 hours before exercise. Kidney protection during contrast studies: 1 mL/kg/hour for 12 hours before or 3 mL/kg/hour for 1 hour before angiography, followed by 1 mL/kg/hour for 6-12 hours after the procedure.
• +Acetylcysteine1 bron🟢Acetylcysteine Eg Sach 10x600mg€ 6,02🟢Lysomucil 600 Tabl 10 X 600 Mg€ 6,36🟢Acetylcysteine Eg 600mg Bruistabl 10x600mg€ 6,47Meer uit 18 →
  About the substance

  Acetylcysteine is a mucolytic that breaks the sulfur bridges in the protein structure of mucus. Through this chemical splitting, the thick mucus becomes more fluid and less viscous. This allows the mucus to be coughed up and cleared from the airways more easily.
• +Calcium Carbonate1 bron🟢Restofit Pulv Sol Buv Sach 30 X 10g€ 18,80🟢Becozyme Comp Eff - Bruistabl 30€ 22,38🟢Calcichew Comp 120x500mg€ 27,61Meer uit 39 →
  About the substance

  Calcium carbonate is an antacid that neutralizes stomach acidity. It reacts chemically with the hydrochloric acid present in the stomach, forming water, carbon dioxide, and calcium chloride. This increases the pH level in the stomach, providing immediate relief from a burning sensation.

  Dosage: Take 1 to 2 tablets when symptoms occur; maximum 6 tablets per day.
• +Phenylephrine1 bron🟠Rhinathiol Antirhinitis Tabl 40€ 9,72
  About the substance

  Potent alpha-1 adrenergic receptor agonist that induces arterial and venous vasoconstriction.

  Dosage: Intravenous bolus injection: 50 to 100 micrograms repeatedly until the desired result is achieved.
• +Aspirin1 bron🟠Sedergine 325mg Bruistabl 20 Nf€ 3,09
  About the substance

  Non-selective cyclooxygenase (COX) inhibitor that blocks the synthesis of prostaglandins and thromboxanes, leading to analgesic, antipyretic, anti-inflammatory, and antiplatelet effects.

  Dosage: Pain/fever: every 4 to 6 hours as needed. Cardiovascular prevention: usually once daily.
• +Caffeine1 bron🟠Mann 500mg/50mg Zakjes 16€ 3,45🟠Mann Pulv Sach 16€ 3,45🟠Wit Kruis 500mg/50mg Zakjes 20 Nf€ 3,61Meer uit 13 →
  About the substance

  Caffeine is a methylxanthine that acts as a non-selective antagonist of adenosine receptors, leading to stimulation of the central nervous system and increased respiratory activity.

  Dosage: Adults: 100-250 mg daily for alertness/headache; 300 mg for post-epidural headache; 9 mg/kg for asthma; 1.6-10 mg/kg for sports performance.
• +Diphenhydramine1 bron🟢Nustasium Comp 20€ 14,90
  About the substance

  First-generation H1-receptor antagonist from the ethanolamine series that competitively blocks histamine H1-receptors in both the periphery and the central nervous system.

  Dosage: Apply only small amounts to the irritated skin using a gentle massage; use for a maximum of 7 days without medical advice.
• +Sodium Chloride1 bron🟢Siroxyl Sirop Enfants/kinderen 125ml 100 Mg/5 Ml€ 4,53🟢Laxido Sinaas Impexeco Pdr Zakje 50 X 13,8g Pip€ 23,45🟢Donacom Pdr Voor Drank Zakje 90 X 1178mg Pip€ 39,95Meer uit 4 →
  About the substance

  Sodium chloride is an isotonic salt mixture that matches the concentration in human blood. It restores the electrolyte balance and causes an increase in intravascular volume. This supports circulation without damaging cells through osmotic pressure differences.
• +Hydrocortisone1 bron🟢Conforma Hydrocortisone 10mg/g Creme 30g€ 7,95🟢Conforma Hydrocortisone Creme 1% 30g€ 9,49🟢Zovirax Duo Crème (magistrale Bereiding) 10 G€ 10,00
  About the substance

  A glucocorticoid that works by binding to glucocorticoid receptors, leading to powerful anti-inflammatory, immunosuppressive, and metabolic effects.

  Dosage: Variable per indication: skin problems 1-4 times daily, mouth ulcers 2-3 times daily, colitis/proctitis 1-2 times daily for 2-3 weeks.

+ Enkel op voorschrift — bespreek met je arts

• +Methadone Hydrochloride1 bronop voorschrift — vraag je arts
• +Ziconotide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ziconotide is an N-type calcium channel-blocking peptide. By inhibiting these channels in neurons, the release of nociceptive neurotransmitters in the dorsal horn of the spinal cord is blocked, leading to a powerful analgesic effect.

  Dosage: Continuous intrathecal infusion: starting dose maximum 2.4 mcg/day. Titration in steps of maximum 2.4 mcg/day at intervals of at least 24-48 hours. Maximum dose 21.6 mcg/day.
• +Nefopam1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-opioid analgesic with a unique mechanism of action that acts as a central monoamine reuptake inhibitor (serotonin, norepinephrine, and dopamine).
• +Ropivacaine hydrochloride1 bronniet vrij verkrijgbaar — vraag je arts
• +Anileridine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic opioid analgesic that acts as an agonist on opioid receptors in the central nervous system (CNS) to suppress pain perception.
• +Aspirin / Caffeine / Propoxyphene1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Aspirin / Codeine1 bronop voorschrift — vraag je arts
• +Tiropramide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tiropramide is an antispasmodic that relaxes smooth muscles by lowering the intracellular calcium concentration. Unlike classic anticholinergics, it does not work via muscarinic receptors, but directly on the muscle cell membrane. This reduces the contraction force and frequency of cramps without significantly affecting salivation or heart rate.
• +Propyphenazone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Propyphenazone is a pyrazolone derivative with analgesic and antipyretic properties. It inhibits the synthesis of prostaglandins in the central nervous system by interacting with the enzyme cyclooxygenase. This raises the pain threshold and influences the thermoregulatory center in the hypothalamus to lower body temperature.
• +Strontium-891 bronniet vrij verkrijgbaar — vraag je arts
• +Sodium Salicylate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes, leading to a reduced synthesis of prostaglandins.
• +Alphaprodine1 bronniet vrij verkrijgbaar — vraag je arts
• +Tiaprofenic acid1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tiaprofenic acid belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). It blocks the enzymes cyclooxygenase-1 and -2, thereby inhibiting the production of prostaglandins. Because prostaglandins are mediators of pain, fever, and inflammation, this inhibition leads to a decrease in swelling, redness, and pain.
• +Levomethadyl1 bronniet vrij verkrijgbaar — vraag je arts
• +Homatropine / Hydrocodone1 bronniet vrij verkrijgbaar — vraag je arts
• +Camphor / Menthol1 bronniet vrij verkrijgbaar — vraag je arts
• +Magaldrate / Simethicone1 bronniet vrij verkrijgbaar — vraag je arts
• +Choline salicylate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Choline salicylate belongs to the salicylate group and acts as a local analgesic and anti-inflammatory agent. It inhibits the enzyme cyclooxygenase, reducing the production of prostaglandins. This decreases pain and local inflammation in the oral mucosa.

  Dosage: Apply a small amount to the painful area as needed; use a maximum of 3 to 4 times daily.
• +Ethoheptazine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ethoheptazine is an opioid analgesic structurally related to pethidine. It works by binding to specific opioid receptors in the central nervous system. This suppresses the transmission of pain signals in the brain and spinal cord, leading to an increased pain threshold.
• +Anhydrous calcium iodide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Anhydrous calcium iodide is an inorganic compound that stimulates the secretion of the mucous membranes in the airways. Due to increased fluid production, thick mucus in the bronchi becomes thinner and more fluid, making it easier to cough up mucus from the airways.
• +Chlorophyllin copper complex1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Chlorophyllin-copper complex is a water-soluble derivative of chlorophyll. It works by neutralizing odor-causing substances in the gut or upon contact with body fluids. The complex binds to these substances, masking or eliminating the unpleasant odor.
• +Dexketoprofen1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits pain, inflammation, and fever by inhibiting the cyclooxygenase enzyme, which leads to reduced synthesis of prostaglandins from arachidonic acid.

  Dosage: Oral: 12.5 mg 4-6 times daily or 25 mg 3 times daily (max. 75 mg/day, 30 min before meals). Injection/infusion: 50 mg every 8-12 hours (max. 150 mg/day, max. 2 days).
• +Ketorolac Tromethamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclooxygenase enzymes, leading to reduced synthesis of prostaglandins responsible for pain and inflammation.

  Dosage: Systemic: lowest possible dose, maximum 5 days. Ophthalmic: 1 drop 3 times daily, starting 24 hours before surgery until 3 weeks after.
• +Tiaprofenate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tiaprofenic acid is a non-steroidal anti-inflammatory drug (NSAID) from the propionic acid group. It blocks the enzymes cyclooxygenase-1 and -2, thereby inhibiting the synthesis of prostaglandins. This reduces the inflammatory response, swelling, and pain in the joints.
• +Benzocaine / butamben / Tetracaine1 bronniet vrij verkrijgbaar — vraag je arts
• +Etidocaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Etidocaine is an injectable amide-type local anesthetic that blocks nerve conduction by stabilizing sodium channels in the nerve cell membrane.
• +Calcium Carbonate / Simethicone1 bronniet vrij verkrijgbaar — vraag je arts
• +Dexbrompheniramine / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Ethyl Chloride1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A local anesthetic that causes an intense cold effect on the skin through rapid evaporation, thereby blocking nerve conduction.
• +Fospropofol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Fospropofol is a water-soluble prodrug of propofol. After administration, it is converted by alkaline phosphatases in the blood into the active substance propofol, which activates GABA-A receptors in the brain. This enhances the inhibitory effect of GABA, leading to rapid sedation and loss of consciousness.
• +Articaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Local anesthetic of the amide type that blocks nerve conduction by inhibiting sodium channels in the nerve cell membrane.
• +Aspirin / butalbital / Caffeine / Codeine1 bronop voorschrift — vraag je arts
• +Guaifenesin / Hydrocodone1 bronniet vrij verkrijgbaar — vraag je arts
• +Calcium Carbonate / Magnesium Hydroxide / Simethicone1 bronniet vrij verkrijgbaar — vraag je arts
• +Aluminum Hydroxide / Magnesium Hydroxide / Simethicone1 bronniet vrij verkrijgbaar — vraag je arts
• +Etoricoxib1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Etoricoxib is a selective cyclooxygenase-2 (COX-2) inhibitor that reduces the synthesis of prostaglandins from arachidonic acid.

  Dosage: Osteoarthritis: 30 mg once daily (max. 60 mg). Rheumatoid arthritis: 60 mg once daily (temporarily max. 90 mg). Use the lowest effective dose for the shortest possible duration.
• +Levorphanol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Levorphanol is a potent synthetic opioid that acts as a strong agonist at both mu- and kappa-opioid receptors. It blocks the transmission of pain signals in the central nervous system and alters the perception of pain. It has a longer duration of action than many other opioids due to its pharmacokinetic properties.
• +Carprofen1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Carprofen is an NSAID that inhibits the synthesis of prostaglandins by selectively inhibiting cyclooxygenase enzymes. It reduces the production of inflammatory mediators, which leads to a decrease in pain and stiffness in joints and soft tissues.
• +Gramicidin / Neomycin / Polymyxin B1 bronniet vrij verkrijgbaar — vraag je arts
• +Levobupivacaine hydrochloride1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Levobupivacaine is an amide-type local anesthetic that blocks sodium channels in nerve cell membranes. This prevents the influx of sodium ions, which stops the formation and conduction of nerve impulses. This results in a temporary, reversible loss of pain sensation in the affected area.
• +Dextromethorphan / Promethazine1 bronniet vrij verkrijgbaar — vraag je arts
• +Chloroprocaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Local anesthetic of the ester type that blocks nerve conduction by increasing the threshold for electrical stimulation, slowing impulse propagation, and reducing the depolarization rate of the action potential.

  Dosage: Spinal anesthesia: 40-50 mg (intrathecal).
• +Dibucaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Dibucaine is a potent amide-type local anesthetic. It stabilizes the neuronal membrane by reducing permeability to sodium ions, thereby blocking nerve conduction. This suppresses pain signals and itching sensations from the skin and mucous membranes.
• +Mepivacaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Local anesthetic of the amide type that blocks nerve conduction by inhibiting sodium channels in the nerve membrane.

  Dosage: Depending on the technique, site of administration, and patient condition; the dosage should be calculated by the clinician to avoid toxic plasma concentrations.
• +Menthol / methyl salicylate1 bronniet vrij verkrijgbaar — vraag je arts
• +Nabumetone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that acts as a prodrug; the active metabolite 6-methoxy-2-naphthylacetic acid inhibits cyclooxygenase (COX) enzymes, leading to reduced prostaglandin biosynthesis.

  Dosage: Adults and children from 14 years: 1 g once daily at bedtime. For acute complaints: starting dose of 1 g, followed by 1 g at bedtime. For severe symptoms: temporarily (max. 15 days) an extra 1 g in the morning.
• +Capsicum oleoresin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Capsicum oleoresin contains capsaicin, a substance that binds to TRPV1 receptors on sensory nerve endings. Initially, this causes a heat sensation, but with repeated use, the receptor becomes depleted and substance P (a neurotransmitter for pain) is exhausted. This blocks the transmission of pain signals to the brain.
• +Antipyrine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Antipyrine is a pyrazolone derivative with analgesic and antipyretic properties. It inhibits the synthesis of prostaglandins in the central nervous system and affects the thermoregulatory center in the hypothalamus. This lowers body temperature and reduces pain perception.
• +Chloroxylenol / pramoxine1 bronniet vrij verkrijgbaar — vraag je arts
• +Icatibant1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Icatibant is a selective, competitive bradykinin B2 receptor antagonist. It blocks the binding of bradykinin to the B2 receptor, thereby inhibiting the vasodilation and increased vascular permeability that lead to angioedema.

  Dosage: Adults: a single 30 mg subcutaneous injection. If there is insufficient effect or recurrence, a second injection may be given after 6 hours, and a third after another 6 hours (max. 90 mg/24h). Children (2-17 years, >12 kg): dosage based on body weight (10 mg to 30 mg).
• +Butylscopolamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Peripherally acting antimuscarinic and anticholinergic agent (quaternary ammonium compound) that relieves spasms in smooth muscle cells of the gastrointestinal, biliary, and urinary systems by blocking parasympathetic ganglia and muscarinic receptors.

  Dosage: Adults and children >12 years: 20-40 mg per dose, maximum 100 mg per day, parenterally (IV, IM, or SC). Children: 0.3-0.6 mg/kg per dose, maximum 1.5 mg/kg per day, parenterally.
• +Crab allergenic extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This extract contains specific crab proteins that trigger an immune response in sensitive individuals. In a skin test, a small amount is applied to see if the immune system has produced antibodies (IgE) against these allergens. A positive reaction confirms an allergic sensitization to crab.
• +Antipyrine / Benzocaine1 bronniet vrij verkrijgbaar — vraag je arts
• +Methotrimeprazine1 bronop voorschrift — vraag je arts
  About the substance

  Methotrimeprazine is a phenothiazine derivative that acts as an antagonist on multiple receptors, including dopamine (D2), histamine (H1), and muscarine (M1) receptors. By blocking these receptors in the brain, it has a strong sedative, antipsychotic, and analgesic effect. It influences signal transmission in areas responsible for emotions and pain processing.
• +Phenyl salicylate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Phenyl salicylate is an ester of salicylic acid and phenol. In the intestines, it is split into these two components. Salicylic acid acts as an anti-inflammatory and pain reliever, while the released phenol has a mild antiseptic effect in the urinary tract.
• +Nitrous oxide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Nitrous oxide belongs to the class of inhalation anesthetics. It works by interacting with NMDA receptors in the central nervous system and influences the release of endogenous opioids. This leads to an increased pain threshold and a calming effect without complete loss of consciousness.
• +Morphine / Naltrexone1 bronniet vrij verkrijgbaar — vraag je arts
• +Chlorpheniramine / Hydrocodone1 bronniet vrij verkrijgbaar — vraag je arts
• +Dyclonine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Dyclonine is a local anesthetic that blocks the conduction of nerve impulses by reducing the permeability of the neuronal membrane to sodium ions.
• +Procaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ester-type local anesthetic that blocks nerve conduction by stabilizing sodium channels in the cell membrane.

  Dosage: To be administered exclusively parenterally by a healthcare professional as an injection for local anesthesia.
• +Remifentanil1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Remifentanil is a potent, ultra-short-acting synthetic µ-opioid agonist. It works by activating µ-opioid receptors, leading to analgesia and a reduction in sympathetic tone.

  Dosage: Induction: continuous i.v. infusion 0.5–1 microg/kg/min, possibly with a bolus of 1 microg/kg (min. 30 sec). Maintenance: 0.25–0.4 microg/kg/min, up to a maximum of 2 microg/kg/min.
• +Chlorphenesin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant; the exact mechanism of action is unknown.
• +Acetaminophen / Propoxyphene1 bronniet vrij verkrijgbaar — vraag je arts
• +Trichlorofluoromethane1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Trichlorofluoromethane is a chlorofluorocarbon (CFC). It has no pharmacological effect on the human body but served only as a physical aid to nebulize medication from a metered-dose inhaler.
• +Difluprednate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A topical corticosteroid (butyrate ester of 6α, 9α-difluorprednisolone acetate) that induces anti-inflammatory effects by binding to glucocorticoid receptors.

  Dosage: Start 24 hours after surgery: 4 times daily for 2 weeks, followed by 2 times daily for 1 week.
• +Codeine / Phenylephrine / Pyrilamine1 bronop voorschrift — vraag je arts
• +Camphor / Eucalyptus oil / Menthol1 bronniet vrij verkrijgbaar — vraag je arts
• +Lobster allergenic extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This extract contains specific proteins from lobster that trigger an immune response in sensitized individuals. When administered into the skin, these proteins bind to IgE antibodies on mast cells, leading to the release of histamine and a local inflammatory reaction.
• +Amitriptyline Hydrochloride1 bronop voorschrift — vraag je arts
  About the substance

  Tricyclic antidepressant that inhibits the reuptake of norepinephrine and serotonin, and also possesses ion channel blocking effects (sodium, potassium, NMDA) and anticholinergic properties.

  Dosage: Adults (depression): starting dose 25 mg twice daily, gradually increased to a maximum of 150 mg per day.
• +Tiludronic acid1 bronop voorschrift — vraag je arts
  About the substance

  Tiludronic acid belongs to the bisphosphonates. It attaches to bone mineral and is absorbed by osteoclasts, the cells that break down bone. This blocks the enzymatic activity of these cells, leading to a decrease in bone resorption.
• +Gramicidin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A peptide antibiotic derived from Bacillus brevis belonging to tyrothricin; it works by disrupting the bacterial cell membrane of gram-positive organisms.
• +Trichloroacetaldehyde1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Trichloroacetaldehyde is a reactive aldehyde that is converted into active metabolites in the body. It acts on the central nervous system by enhancing the activity of GABA receptors, leading to sedation and sleep induction.
• +Dalfampridine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Dalfampridine is a potassium channel blocker. By blocking potassium channels in demyelinated nerve fibers, the repolarization of the nerve cell is delayed, which prolongs the action potential. This improves the conduction of nerve impulses along damaged nerve pathways.
• +Acetaminophen / salicylamide1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Caffeine1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / dexbrompheniramine / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Caffeine / Guaifenesin / Phenylephrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Chlorpheniramine / Phenylephrine / salicylam1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Caffeine / phenyltoloxamine / salicylamide1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Pseudoephedrine / Triprolidine1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Pentazocine1 bronniet vrij verkrijgbaar — vraag je arts
• +Mefenamic Acid1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A non-steroidal anti-inflammatory drug (NSAID) that acts as an inhibitor of the cyclooxygenase enzyme, thereby blocking the synthesis of prostaglandins.

  Dosage: Take every 6 hours with food, for a maximum of 1 week.
• +Tetracaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Local anesthetic of the ester type that blocks sodium channels in nerve cells, thereby interrupting the initiation and conduction of nerve impulses.
• +Alfentanil1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Alfentanil is a very fast-acting, short-duration opioid anesthetic of the 4-anilinopiperidine class. It acts as a potent agonist on opioid receptors in the central nervous system, leading to rapid analgesia and respiratory depression.

  Dosage: Individually determined based on age, weight, physical condition, and type of procedure; administered via intravenous bolus injection or infusion. In elderly and debilitated patients, the initial dose should be reduced.
• +Triflupromazine1 bronop voorschrift — vraag je arts
  About the substance

  Triflupromazine is a phenothiazine antipsychotic that acts as a dopamine D2 receptor antagonist in the central nervous system.
• +Acetylcarnitine1 bronop voorschrift — vraag je arts
  About the substance

  Acetylcarnitine is an ester of the amino acid carnitine. It plays a crucial role in transporting fatty acids to the mitochondria for energy production and supports the synthesis of acetylcholine. This helps maintain cellular energy balance and neurotransmission.

  Dosage: The usual dosage is 500 to 1500 mg per day, divided into multiple intakes.
• +Acetaminophen / Caffeine / isometheptene1 bronniet vrij verkrijgbaar — vraag je arts
• +Camphor1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Artichoke leaf-based products contain substances such as cynarin that stimulate bile production in the liver (choleretic effect). Increased bile release into the intestines helps digest fats, which speeds up digestion and reduces symptoms of bloating.
• +Evening primrose extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Evening primrose oil contains gamma-linolenic acid (GLA), an essential omega-6 fatty acid. GLA is a precursor to prostaglandin E1, a substance that has anti-inflammatory properties and can support the skin's barrier function.

  Dosage: The dosage varies significantly per product; always follow the instructions on the packaging.
• +Tuna allergenic extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This extract contains specific allergens from tuna that cause a local immune reaction in allergic patients. By introducing the extract into the skin, present IgE antibodies react, resulting in visible swelling and redness.
• +Methylsulfonylmethane1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Methylsulfonylmethane (MSM) is an organic sulfur compound. Sulfur is an essential component for the formation of collagen and keratin in cartilage and connective tissue. It is believed to have anti-inflammatory effects and to support the integrity of joint tissue.

  Dosage: Usual dosage is 1000 to 3000 mg per day, preferably during meals.
• +Sufentanil1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Sufentanil is a potent, synthetic opioid that acts as a full agonist at the μ-opioid receptors in the central nervous system.

  Dosage: Exclusively for professional administration in a medically controlled setting; dosage is strictly individual and depends on the route of administration (intravenous, epidural, or sublingual).
• +Abarelix1 bronop voorschrift — vraag je arts
  About the substance

  Synthetic gonadotropin-releasing hormone (GnRH) antagonist that directly blocks the release of luteinizing hormone and follicle-stimulating hormone.

  Dosage: The maximum dose in clinical trials was 150 mg.
• +Sulfapyridine1 bronop voorschrift — vraag je arts
  About the substance

  Sulfonamide antibiotic that inhibits bacterial folic acid synthesis by competing with para-aminobenzoic acid (PABA).
• +Isometheptene1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Sympathomimetic amine that induces vasoconstriction through stimulation of the sympathetic nervous system.

  Dosage: At the onset of headache, maximum 5 capsules per 12 hours and maximum 8 capsules per day.
• +Pamabrom1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Pamabrom is a diuretic that promotes the excretion of water and salts via the kidneys. By slightly increasing renal blood flow and inhibiting sodium reabsorption, it helps remove excess fluid from the body.

  Dosage: Usual dosage is 50 mg per dose, maximum 200 mg per day.
• +Hydrocodone / Phenylephrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Lidocaine / Prilocaine1 bronniet vrij verkrijgbaar — vraag je arts
• +Etodolac1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis by inhibiting cyclooxygenase enzymes.

  Dosage: Arthritis: 2-3 times daily tablets/capsules or once daily extended-release. Pain: every 6 to 8 hours.
• +Prilocaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Amide-type local anesthetic that reversibly inhibits the excitability of nerve fibers and pain receptors by affecting ion permeability.

  Dosage: For hospital use only by specialized medical personnel; dosage depends on the chosen anesthetic technique.
• +Codeine / Guaifenesin / Phenylephrine1 bronop voorschrift — vraag je arts
• +Acetaminophen / Caffeine / dihydrocodeine1 bronniet vrij verkrijgbaar — vraag je arts
• +Codeine / Pseudoephedrine1 bronop voorschrift — vraag je arts
• +Hydrocodone / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Febuxostat1 bronop voorschrift — vraag je arts
  About the substance

  Febuxostat is a potent, non-purine, selective inhibitor of the enzyme xanthine oxidase (XO). By inhibiting this enzyme, the conversion of hypoxanthine and xanthine to uric acid is blocked, leading to a decrease in serum uric acid levels.

  Dosage: Starting dose: 80 mg orally once daily, with or without food. If uric acid is >6 mg/dl (357 µmol/l) after 2-4 weeks, the dose can be increased to 120 mg once daily.
• +Guaifenesin / Hydrocodone / Phenylephrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This vaccine contains an attenuated live strain of the varicella-zoster virus. After administration, it stimulates the immune system to produce specific antibodies and T-cells, allowing the body to effectively fight the virus upon future exposure.
• +Guaifenesin / Hydrocodone / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Mestranol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Mestranol is a synthetic estrogen that is converted in the liver into ethinylestradiol. It works by inhibiting the release of gonadotropins (FSH and LH), thereby preventing egg maturation and ovulation.
• +Metaxalone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Metaxalone is a centrally acting muscle relaxant. The exact mechanism of action is not fully understood, but it is believed to promote general depression of the central nervous system. By influencing neuronal transmission in the brain and spinal cord, it reduces muscle tension and associated pain.
• +Naloxone Hydrochloride1 bronop voorschrift — vraag je arts
  About the substance

  Naloxone is a specific opioid antagonist. It binds with higher affinity to mu-opioid receptors in the central nervous system than opioids themselves, without activating these receptors. As a result, it displaces opioids from receptor sites, immediately blocking the effects of the overdose.
• +Alvimopan1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Peripherally acting mu-opioid receptor antagonist that blocks the inhibitory effects of opioids on gastrointestinal motility without affecting central pain relief.

  Dosage: 1 capsule before surgery, followed by 1 capsule twice daily for a maximum of 7 days or until discharge.
• +Aspergillus niger var. niger extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  The extract contains specific proteins and allergens derived from the fungus. When administered to a sensitized individual, these allergens bind to IgE antibodies on mast cells. This process triggers a local immune reaction, leading to the release of histamine and other mediators that cause a visible skin reaction.
• +Safflower Oil1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Safflower oil is rich in polyunsaturated fatty acids, particularly linoleic acid. These fatty acids play a role in lowering blood LDL cholesterol levels by influencing fatty acid metabolism in the liver. Additionally, they support cell membrane integrity and the production of anti-inflammatory prostaglandins.

  Dosage: The usual dosage varies by product; consult the packaging and do not exceed the recommended daily amount.
• +Methylnaltrexone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  It is a peripheral opioid receptor antagonist. It blocks the action of opioids specifically in the intestines, without affecting the pain-relieving effect in the brain. This restores intestinal movement that was slowed down by the painkillers.
• +Penciclovir1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic acyclic guanine derivative and nucleoside analogue that inhibits viral DNA polymerase, thereby blocking the viral replication of herpes simplex viruses.

  Dosage: Cream: apply every 2 hours for 4 days, only during waking hours.
• +Fenugreek seed preparation1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Fenugreek contains soluble fibers, such as galactomannan, which slow down the absorption of carbohydrates in the intestines. This flattens the rise in blood sugar levels after a meal. Additionally, it contains substances that may improve insulin sensitivity and support milk production through hormonal stimulation.

  Dosage: Follow the instructions on the packaging; for diabetes, use only in consultation with a doctor due to its effect on blood sugar levels.
• +Poppy seed allergenic extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  The extract contains specific protein fractions of poppy seeds that have stimulated the production of IgE antibodies in allergic individuals. When the extract is introduced into the skin, these allergens bind to IgE receptors on mast cells. This causes degranulation of the mast cell, resulting in a local inflammatory reaction that confirms the allergy.
• +Nepafenac1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) that is converted into amfenac after ocular administration. This inhibits the enzyme cyclooxygenase (prostaglandin-H-synthase), thereby suppressing the synthesis of prostaglandins.

  Dosage: 1 drop in the affected eye once daily, starting the day before surgery, on the day of surgery, and for 2 to 3 weeks thereafter. An additional drop is required 30 to 120 minutes before surgery.
• +Ammonium Chloride / Chlorpheniramine / Codeine / Phenylephri1 bronop voorschrift — vraag je arts
• +Eletriptan1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Eletriptan is a selective 5-HT1 receptor agonist that combats migraine through vasoconstriction of cerebral blood vessels and inhibition of pro-inflammatory neuropeptide release via neuronal 5-HT1B/1D receptors.

  Dosage: Starting dose 40 mg at the onset of the headache phase; maximum 2 tablets per 24 hours.
• +Meperidine / Promethazine1 bronniet vrij verkrijgbaar — vraag je arts
• +Alefacept1 bronop voorschrift — vraag je arts
  About the substance

  Immunosuppressive dimeric fusion protein that blocks the interaction between LFA-3 and CD2, thereby inhibiting the activation and proliferation of T-lymphocytes.

  Dosage: One intramuscular or intravenous injection per week for 12 weeks; a second 12-week cycle is possible after a break of at least 12 weeks.
• +Mefenamate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This medication belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). It inhibits the enzymes cyclooxygenase-1 and -2 (COX-1 and COX-2), which are responsible for the synthesis of prostaglandins. By lowering the production of these inflammatory mediators, it reduces both pain and uterine contractions.
• +Abiraterone1 bronop voorschrift — vraag je arts
  About the substance

  Selective and irreversible inhibitor of the enzyme 17α-hydroxylase/C17,20-lyase (CYP17), which is essential for the biosynthesis of androgens in the testes, adrenal glands, and prostate tumors.

  Dosage: 1,000 mg once daily, to be taken on an empty stomach.
• +Phenylephrine / Promethazine1 bronniet vrij verkrijgbaar — vraag je arts
• +Chondroitin Sulfates1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Chondroitin is a natural component of cartilage tissue. It works by retaining water in the cartilage matrix, which improves elasticity and shock-absorbing properties. Additionally, it inhibits enzymes that break down cartilage, which can slow the process of degeneration.

  Dosage: The usual dosage is 800 to 1200 mg per day, divided into one or more intakes.
• +Chlorpheniramine / Hydrocodone / Phenylephrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Dinoprost1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Dinoprost is a naturally occurring prostaglandin F2-alpha. It binds to specific prostaglandin receptors in the smooth muscle of the uterus, leading to powerful contractions. This softens the cervix and stimulates the uterus to expel its contents.
• +Capsicum extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  The active ingredient capsaicin binds to TRPV1 receptors on sensory nerve endings in the skin. Initially, this causes a sensation of heat, but with repeated use, the nerve becomes depleted of the neurotransmitter 'substance P'. As a result, the pain signal is no longer effectively transmitted to the brain.

  Dosage: Apply a thin layer to the painful area, maximum 3-4 times per day; wash hands thoroughly after use.
• +Chlorpheniramine / Codeine / Pseudoephedrine1 bronop voorschrift — vraag je arts
• +Codeine / Guaifenesin / Pseudoephedrine1 bronop voorschrift — vraag je arts
• +Cyclobenzaprine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant with a structure related to tricyclic antidepressants; it works by influencing motor activity in the brainstem.

  Dosage: Tablets: 2-4 times daily; extended-release capsules: 1-2 times daily. Maximum duration of use: 3 weeks.
• +Desflurane1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Halogenated methyl ethyl ether for inhalation; acts as a general anesthetic by suppressing the central nervous system, leading to loss of consciousness, sedation, and reduction of autonomic reflexes.

  Dosage: Administration via inhalation using a specific vaporizer; dosage should be individualized based on patient response.
• +Amlexanox1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Anti-allergic agent that inhibits the release of histamine and leukotrienes from mast cells and suppresses inflammatory mediators.

  Dosage: Apply 0.6 cm of paste to the ulcer 4 times daily, after brushing and flossing (after breakfast, lunch, dinner, and before bedtime), for a maximum of 10 days.
• +Samarium1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Samarium-153 is a radioactive isotope that accumulates in areas of increased bone activity, such as bone metastases. It emits beta radiation that locally damages and destroys surrounding cancer cells. This reduces pressure on bone tissue and nerve endings, leading to pain relief.
• +Strontium1 bronop voorschrift — vraag je arts
  About the substance

  Radiopharmaceutical that settles in bone tissue as a calcium analog and emits beta radiation there, leading to local irradiation of bone metastases for pain relief.

  Dosage: Intravenous administration by a healthcare professional.
• +Oyster allergenic extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  The extract contains specific proteins from oysters that trigger an immune response in sensitive individuals. During a skin test, these proteins bind to IgE antibodies on mast cells in the skin. This process activates the mast cells to release histamine, resulting in local swelling and redness as a sign of an allergic reaction.
• +Clioquinol / Hydrocortisone / pramoxine1 bronniet vrij verkrijgbaar — vraag je arts
• +Dronabinol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic form of delta-9-tetrahydrocannabinol (THC) that acts as a weak partial agonist at the cannabinoid-1 (CB1R) and cannabinoid-2 (CB2R) receptors.

  Dosage: Chemotherapy: 1-3 hours before the treatment, then every 2-4 hours (total 4-6 doses per day). Anorexia: twice daily before meals or once daily in the evening.
• +Benzydamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Locally acting non-steroidal anti-inflammatory drug (NSAID) with local anesthetic properties; it works by providing local pain relief and reducing inflammation in the mouth, throat, or musculoskeletal system.

  Dosage: Cream: Apply to the affected area 1-4 times daily.
• +Bupivacaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  An amide-type local anesthetic that blocks sodium channels in nerve fibers, interrupting the conduction of pain signals and motor impulses.

  Dosage: Depending on the technique and patient factors; consult standard reference works for specific dosage schedules.
• +Ketoprofen1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) from the propionic acid derivative group. It works by inhibiting the enzyme cyclooxygenase (COX), leading to reduced synthesis of prostaglandins, which are the mediators of pain, fever, and inflammation.

  Dosage: 25 mg 1–3 times daily; if necessary, start with 50 mg; maximum 100 mg per day. Take during meals with a glass of water.
• +Bromfenac1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Bromfenac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclooxygenase (COX), which leads to a reduced synthesis of prostaglandins and thereby provides an anti-inflammatory and analgesic effect.

  Dosage: One drop in the affected eye once daily, starting one day before surgery, on the day of surgery, and for 14 days thereafter.
• +Almotriptan1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Selective 5-HT1B/1D receptor agonist. It works by constricting cranial blood vessels and inhibiting the trigeminovascular inflammatory response.

  Dosage: 12.5 mg at the onset of the headache. If symptoms return within 24 hours, a second dose may be taken (minimum interval 2 hours). Maximum 2 tablets per 24 hours.
• +Fructose1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A monosaccharide (six-carbon sugar) that acts as a carbohydrate source for parenteral nutrition and energy supply.

  Dosage: To be determined individually based on age, weight, and clinical condition; for adults, 500 ml to 3 liters per 24 hours.
• +Naratriptan1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Naratriptan is a selective 5-HT1 receptor agonist (triptan) that achieves vasoconstriction of intracranial blood vessels through stimulation of 5-HT1B/1D receptors.

  Dosage: 1 tablet of 2.5 mg at the onset of the headache. For recurring symptoms, a second dose of 2.5 mg may be taken after at least 4 hours; maximum 5 mg per 24 hours.
• +Promethazine Hydrochloride1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Promethazine is a phenothiazine derivative that acts as an antagonist on various receptors, including histamine H1 receptors, muscarinic acetylcholine receptors, and dopamine D2 receptors.

  Dosage: Adults (allergy): 15-150 mg per day in divided doses during meals and at bedtime. Motion sickness (adults/children >8 years): 25 mg, 0.5-1 hour before departure, repeat after 8 hours if necessary. Children >2 years (allergy): 0.2 mg/kg 2-4 times per day.
• +Chlorpheniramine / Codeine1 bronop voorschrift — vraag je arts
• +Brompheniramine / Codeine / Phenylephrine1 bronop voorschrift — vraag je arts
• +Anakinra1 bronop voorschrift — vraag je arts
  About the substance

  Anakinra is a recombinant interleukin-1 (IL-1) receptor antagonist that neutralizes the biological activity of IL-1α and IL-1β by competitively binding to the IL-1 type I receptor. This inhibits the pro-inflammatory cascade responsible for synovial inflammation and immune response.

  Dosage: 100 mg once daily via subcutaneous injection, daily at the same time.
• +Acetaminophen / Dextromethorphan / Guaifenesin1 bronniet vrij verkrijgbaar — vraag je arts
• +Chlorpheniramine / Codeine / Phenylephrine1 bronop voorschrift — vraag je arts
• +Acetaminophen / phenyltoloxamine1 bronniet vrij verkrijgbaar — vraag je arts
• +Meloxicam1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) of the oxicam class, which acts as a preferential COX-2 inhibitor by blocking the biosynthesis of prostaglandins.

  Dosage: 7.5 mg per day, to be taken as a single daily dose.
• +Proparacaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Proparacaine is an ester-type local anesthetic. It blocks sodium channels in the nerve membranes of the cornea and conjunctiva, temporarily interrupting the conduction of pain signals to the brain. This results in rapid and short-term numbness of the eye surface.
• +Milnacipran1 bronop voorschrift — vraag je arts
  About the substance

  A selective serotonin and norepinephrine reuptake inhibitor (SNRI) with relatively balanced inhibition and a slight preference for norepinephrine, which contributes to the modulation of pain signals.

  Dosage: Twice daily, with a gradual dose increase in the first week.
• +Pancuronium1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A bis-quaternary steroid and competitive nicotine antagonist that acts as a non-depolarizing neuromuscular blocking agent.
• +Diphenoxylate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A meperidine congener and opioid agonist that inhibits intestinal motility by acting on opioid receptors in the gastrointestinal tract.
• +Acetaminophen / Dextromethorphan1 bronniet vrij verkrijgbaar — vraag je arts
• +Piroxicam1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the cyclooxygenase enzyme, leading to reduced synthesis of prostaglandins.

  Dosage: The maximum recommended daily dose is 20 mg.
• +Fenoprofen1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes, leading to reduced synthesis of prostaglandins with anti-inflammatory, analgesic, and antipyretic effects.

  Dosage: For arthritis: 3 to 4 times daily. For pain: every 4 to 6 hours as needed. Take with a full glass of water, preferably during meals or with milk/antacids to reduce stomach upset.
• +Diflunisal1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A salicylate derivative and non-steroidal anti-inflammatory drug (NSAID) that inhibits pain, inflammation, and fever by inhibiting prostaglandin synthesis via the arachidonic acid pathway.

  Dosage: Take tablets every 8 to 12 hours with water, milk, or food; swallow whole without chewing or crushing.
• +Tegaserod1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tegaserod is a selective 5-HT4 receptor agonist that promotes intestinal motility by acting on serotonin-4 receptors in the smooth muscle cells of the gastrointestinal tract, leading to increased peristalsis and secretion.

  Dosage: 1 tablet twice daily, to be taken on an empty stomach shortly before a meal.
• +Zolmitriptan1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Zolmitriptan is a selective 5-HT1B/1D receptor agonist from the triptan class. It works by stimulating these receptors, which leads to vasoconstriction of blood vessels.

  Dosage: 2.5 mg at the onset of the migraine; if symptoms return within 24 hours, a second dose may be taken, with an interval of at least 2 hours.
• +Curcumin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Curcumin is the active substance from turmeric and acts as a natural anti-inflammatory. It inhibits various enzymes and transcription factors (such as NF-kB) involved in the production of inflammatory mediators. This dampens the inflammatory response in the body.
• +Chlorzoxazone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant that inhibits muscle spasms by acting on the spinal cord and subcortical brain areas.

  Dosage: Take orally 3 to 4 times daily.
• +Hydrocodone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic opioid derivative of codeine that acts as an agonist on opioid receptors in the central nervous system.

  Dosage: Immediate-release forms: every 4-6 hours; long-acting forms: every 12 hours.
• +Rizatriptan1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Selective 5-HT1B/1D receptor agonist. It works by stimulating these serotonin receptors, leading to vasoconstriction of intracranial blood vessels and inhibition of pro-inflammatory neuropeptide release.

  Dosage: Maximum 30 mg per 24 hours (maximum 15 mg per 24 hours when used concomitantly with propranolol). A second dose may be taken 2 hours after the first if necessary.
• +Amitriptyline / Chlordiazepoxide1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / phenyltoloxamine / salicylamide1 bronniet vrij verkrijgbaar — vraag je arts
• +Hemin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Hemin is an iron-containing protoporphyrin IX (heme B) that acts as an inhibitor of the enzyme ALA synthase, the rate-limiting step in heme synthesis.
• +Acetaminophen / Dextromethorphan / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Methoxyflurane1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Inhalation anesthetics that depress the central nervous system to achieve analgesia and anesthesia.
• +Valdecoxib1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Selective COX-2 inhibitor (NSAID) that inhibits the synthesis of prostaglandins through selective inhibition of the cyclooxygenase-2 enzyme.
• +Alosetron1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Alosetron is a selective 5-HT3 receptor antagonist that modulates serotonin-sensitive gastrointestinal processes.

  Dosage: Twice daily orally; start with a low dose and evaluate after 4 weeks.
• +Acetaminophen / Brompheniramine / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Tenoxicam1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that acts as a potent inhibitor of cyclooxygenase-1 (COX-1) and -2 (COX-2) enzymes, thereby blocking the biosynthesis of prostaglandins.

  Dosage: 20 mg once daily, to be taken with a glass of water during a meal.
• +Flavoxate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  An antispasmodic for the urogenital system that works through direct relaxation of smooth muscle cells, a local anesthetic effect, and possibly muscarinic antagonism.

  Dosage: Adults: 1 tablet 3 to 4 times daily, to be taken after meals with water. In case of kidney failure: 2 to 3 tablets per day.
• +4-Aminobenzoic Acid1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  PABA acts as a UV filter by absorbing ultraviolet radiation (specifically UVB) before it reaches the deeper layers of the skin. This reduces the formation of sunburn and DNA damage in skin cells. As a supplement, it is sometimes used for connective tissue disorders, although the mechanism of action for this is less clear.

  Dosage: Follow the instructions on the specific product; for sunscreens, apply generously and regularly.
• +Acetaminophen / Chlorpheniramine / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Dextromethorphan / Guaifenesin / Pseudoephed1 bronniet vrij verkrijgbaar — vraag je arts
• +Pentosan Polysulfate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This medication belongs to the class of heparinoids and acts as a protective layer for the bladder lining. It attaches to the damaged urothelial layer and restores the barrier function, causing irritants in the urine to have less contact with the underlying nerve endings. This reduces pain and the urge to urinate.
• +Acetaminophen / Chlorpheniramine / Codeine / Phenylephrine1 bronop voorschrift — vraag je arts
• +Meclofenamate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This medication is an NSAID that blocks the synthesis of prostaglandins by inhibiting the enzymes COX-1 and COX-2. By lowering the concentration of these inflammatory mediators, it reduces pain, swelling, and stiffness in joints and tissues. It also has a direct effect on the uterus for menstrual pain.
• +Paregoric1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Paregoric contains opium alkaloids, including morphine. These substances bind to opioid receptors in the intestinal wall, which slows down intestinal peristalsis (the movement of the intestines). This increases the transit time of intestinal contents, which promotes water absorption and reduces the frequency of bowel movements.
• +Chloroxylenol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  An antiseptic from the substituted phenol class; it acts as a bactericide by disrupting the bacterial cell wall.

  Dosage: For cutaneous use: 50 ml diluted with water to 1 liter (5% solution); do not use undiluted.
• +Acetaminophen / Dextromethorphan / Doxylamine / Pseudoephedr1 bronniet vrij verkrijgbaar — vraag je arts
• +Probenecid1 bronop voorschrift — vraag je arts
  About the substance

  Uricosuric agent that inhibits renal tubular reabsorption of urate and blocks the renal excretion of organic anions.

  Dosage: Maintenance for gout: starting dose 250 mg twice daily, potentially increased in steps to a maximum of 2-3 g per day in 2 doses. With antibiotics: 4 times daily.
• +Naproxen / Sumatriptan1 bronniet vrij verkrijgbaar — vraag je arts
• +Fentanyl1 bronop voorschrift — vraag je arts
  About the substance

  Fentanyl is a potent opioid agonist that works by interacting with opioid receptors in the central nervous system, suppressing pain signals in the thalamus and hypothalamus.

  Dosage: Individually determined based on patient factors and type of procedure; for pain sensation neutralization, 0.002 to 0.008 mg/kg intravenously is advised.
• +Droperidol1 bronop voorschrift — vraag je arts
  About the substance

  Droperidol is a butyrophenone neuroleptic that acts as a potent dopamine-D2 antagonist with weak alpha-adrenolytic properties.

  Dosage: Intravenous administration: adults 0.625-1.25 mg; elderly and patients with liver/kidney impairment 0.625 mg; children (2-11 years) and adolescents 10-50 micrograms/kg (max. 1.25 mg).
• +Lanolin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Lanolin is a natural fat derived from sheep's wool that is very similar to human skin lipids. It acts as an occlusive agent, meaning it forms a protective barrier on the skin that prevents moisture loss. This hydrates the skin and allows the natural repair process of the skin barrier to take place undisturbed.

  Dosage: Apply thinly to the affected skin as needed; for nipple fissures, apply after every feeding.
• +Calcium polycarbophil1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A synthetic polymer and stool stabilizer that regulates stool consistency through an exceptionally high water-binding capacity.
• +Teriparatide1 bronop voorschrift — vraag je arts
  About the substance

  Recombinant parathyroid hormone (PTH) analog and osteoanabolic agent; it stimulates bone formation by acting directly on osteoblasts and increases calcium resorption in the intestines and kidneys.

  Dosage: 20 micrograms once daily via injection, with a maximum total treatment duration of 24 months over the entire lifetime.
• +Oxaprozin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes, leading to reduced synthesis of prostaglandins.

  Dosage: To be taken once or twice daily.
• +Famotidine / Ibuprofen1 bronniet vrij verkrijgbaar — vraag je arts
• +Lidocaine Hydrochloride1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This medication belongs to the class of amide-type local anesthetics. It blocks the sodium channels in nerve cell membranes, temporarily interrupting the conduction of pain signals to the brain. This results in local numbness that makes performing medical procedures on the eye painless.
• +Esomeprazole / Naproxen1 bronniet vrij verkrijgbaar — vraag je arts
• +Etidronate1 bronop voorschrift — vraag je arts
  About the substance

  Etidronate is a bisphosphonate that inhibits bone resorption by acting on osteoclasts, the cells that break down bone tissue. It binds to hydroxyapatite in the bone and prevents osteoclasts from attaching or performing their enzymatic activity. This leads to a slowing of bone remodeling, keeping the bone structure more stable.
• +Protriptyline1 bronop voorschrift — vraag je arts
  About the substance

  This medication is a tricyclic antidepressant that inhibits the reuptake of the neurotransmitters norepinephrine and serotonin in the synaptic cleft. By increasing the concentration of these substances in the brain, communication between nerve cells is improved. This process helps regulate mood and reduce depressive symptoms.
• +Ketamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ketamine is an NMDA receptor antagonist and anesthetic that induces dissociative anesthesia by reducing activity in the neocortex and thalamus, combined with increased activity in the limbic system.

  Dosage: No standard dosage schedule; administered via injection or intravenous infusion, depending on the procedure and desired duration.
• +Natalizumab1 bronop voorschrift — vraag je arts
  About the substance

  Selective inhibitor of adhesion molecules; a humanized monoclonal antibody that binds to the α4 subunit of integrins on leukocytes, blocking their migration through the endothelium into inflammatory tissue.

  Dosage: 300 mg via intravenous infusion, once every four weeks.
• +Acetaminophen / Diphenhydramine1 bronniet vrij verkrijgbaar — vraag je arts
• +Eucalyptus oil1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  The active ingredient in eucalyptus oil is cineole, a volatile compound that provides a cooling effect on the mucous membranes. It acts as an expectorant by lowering the viscosity of mucus in the airways, making it easier to cough up. Additionally, it has mild antiseptic properties that can reduce irritation in the upper respiratory tract.

  Dosage: Add a few drops to hot water for inhalation or apply diluted to the chest; not suitable for young children.
• +Troleandomycin1 bronop voorschrift — vraag je arts
  About the substance

  Macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
• +Pregabalin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Pregabalin is a gamma-aminobutyric acid analog that binds to the α2δ-subunit of voltage-dependent calcium channels in the central nervous system, thereby reducing calcium influx and the release of excitatory neurotransmitters.

  Dosage: 150 to 600 mg per day, divided into two or three doses.
• +Nitroglycerin1 bronop voorschrift — vraag je arts
  About the substance

  Nitroglycerin is converted in the body into nitric oxide (NO). This causes potent relaxation of the smooth muscles in the blood vessels (vasodilation), causing both veins and arteries to dilate. This reduces the workload on the heart and improves blood flow to the heart muscle.
• +Clomipramine1 bronop voorschrift — vraag je arts
  About the substance

  Tricyclic antidepressant (TCA) that inhibits the neuronal reuptake of serotonin and noradrenaline. Additionally, it acts as an antagonist at histamine H1, alpha1-adrenergic, and muscarinic receptors.

  Dosage: To be determined individually. Starting phase: 3 times daily with meals; after several weeks, often once daily before bedtime.
• +Benzyl Alcohol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  As a preservative, it inhibits the growth of bacteria and fungi by disrupting their cell membranes. When used against head lice, it works by blocking the lice's breathing openings, causing them to suffocate. It is an effective way to kill parasites without causing severe skin irritation when used correctly.
• +Mesalamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Mesalamine is an anti-inflammatory agent that acts locally in the intestinal mucosa. It inhibits the production of pro-inflammatory substances such as prostaglandins and leukotrienes by blocking the activity of enzymes like cyclooxygenase and lipoxygenase. This reduces inflammation in the intestinal wall and alleviates symptoms such as diarrhea and abdominal pain.
• +Salsalate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits the synthesis and release of prostaglandins.

  Dosage: One tablet 2 to 3 times a day, to be taken with food or milk.
• +Aprepitant1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Aprepitant is a selective antagonist with high affinity for the human substance P-neurokinin 1 (NK1) receptor. By blocking these receptors in the central nervous system, emetogenic stimulus transmission is suppressed.

  Dosage: 3-day regimen: 1 hour before chemotherapy on day 1, then in the morning on days 2 and 3. For surgery: a single dose within 3 hours before the start.
• +Golimumab1 bronop voorschrift — vraag je arts
  About the substance

  Human monoclonal antibody and TNFα inhibitor. It binds to soluble and transmembrane TNFα, blocking binding to TNFα receptors and neutralizing inflammatory mediators (such as adhesion molecules).

  Dosage: Standard 50 mg subcutaneously once a month on a fixed day; for ulcerative colitis, loading doses apply in weeks 0 and 2.
• +Acetaminophen / Diphenhydramine / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Zidovudine1 bronop voorschrift — vraag je arts
  About the substance

  Zidovudine is a nucleoside analogue (NRTI) that, after intracellular phosphorylation to triphosphate, acts as a chain terminator of viral DNA, thereby inhibiting the replication of the human immunodeficiency virus (HIV).

  Dosage: Adults: 1 or 2 mg/kg every 4 hours via slow intravenous infusion (over 1 hour); oral schedule depends on prescription (usually 3-4 times daily).
• +Tolmetin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes, leading to reduced synthesis of prostaglandins.

  Dosage: Adults: 3 times daily on an empty stomach. Children > 2 years: 3 to 4 times daily on an empty stomach.
• +Lovastatin / Niacin1 bronniet vrij verkrijgbaar — vraag je arts
• +Chlorpheniramine / Ibuprofen / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Nafarelin1 bronop voorschrift — vraag je arts
  About the substance

  Potent synthetic gonadotropin-releasing hormone (GnRH) agonist that downregulates the pituitary-gonadal axis through continuous stimulation.

  Dosage: Endometriosis: 1 spray twice daily (one in each nostril, morning and evening). Precocious puberty: 4 sprays once daily (two in each nostril in the morning).
• +Castor Oil1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  In the intestine, ricinoleic acid is released from the oil. This acid slightly irritates the intestinal wall and directly stimulates intestinal peristalsis, while also inhibiting the absorption of water and electrolytes in the intestine. This leads to a rapid and powerful emptying of the bowels.

  Dosage: Not suitable for self-care without medical supervision due to its powerful effect.
• +Pheniramine / Phenylephrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Norgestimate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This agent mimics the natural hormone progesterone and works by suppressing ovulation through feedback on the pituitary gland. Additionally, it changes the composition of the uterine lining and cervical mucus, making implantation more difficult and hindering sperm passage. This provides reliable protection against unwanted pregnancy.
• +Mycophenolic acid1 bronop voorschrift — vraag je arts
  About the substance

  It is an immunosuppressant that selectively inhibits the proliferation of T and B lymphocytes. It blocks the enzyme inosine monophosphate dehydrogenase, which is essential for the synthesis of guanosine nucleotides required for the cell division of these immune cells. By suppressing the immune response, the risk of donor organ rejection is reduced.
• +Acetaminophen / Diphenhydramine / Phenylephrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Dextromethorphan / Doxylamine1 bronniet vrij verkrijgbaar — vraag je arts
• +Certolizumab pegol1 bronop voorschrift — vraag je arts
  About the substance

  Pegylated monoclonal antibody (Fab fragment) that acts as a selective TNF-alpha inhibitor. By binding to and neutralizing TNF-alpha, the pro-inflammatory cytokine cascade is suppressed.

  Dosage: Loading dose: 400 mg (2 subcutaneous injections of 200 mg) in weeks 0, 2, and 4.
• +Propantheline1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A muscarinic antagonist that acts as an antispasmodic by blocking parasympathetic nerve impulses; at high doses, a nicotine effect also occurs, leading to neuromuscular blockade.

  Dosage: 1 tablet 4 times daily, 30 minutes before meals and at bedtime.
• +Famciclovir1 bronop voorschrift — vraag je arts
  About the substance

  Guanine analogue (nucleoside analogue) that is converted into penciclovir as a prodrug; it inhibits viral DNA polymerase and thereby the replication of herpes viruses.

  Dosage: For shingles: 500 mg 3 times daily (7 days for immunocompetent patients, 10 days for immunocompromised patients). Dose adjustment required for renal impairment.
• +Fluphenazine1 bronop voorschrift — vraag je arts
  About the substance

  A phenothiazine antipsychotic that acts as a dopamine D2 antagonist in the brain.

  Dosage: 2 to 3 times per day as a tablet or oral liquid; intake can be with or without food.
• +Sapropterin1 bronop voorschrift — vraag je arts
  About the substance

  Synthetic form of tetrahydrobiopterin (BH4), an essential cofactor for enzymes that hydroxylate phenylalanine, tyrosine, and tryptophan, and for the synthesis of nitric oxide.

  Dosage: Starting dose 10 mg/kg body weight, once daily, to be taken during a meal.
• +Ammonium Chloride1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ammonium chloride slightly irritates the stomach lining, which stimulates the secretion of mucus in the airways via a reflex, thinning the mucus. Upon systemic absorption, it is converted into urea in the liver, releasing hydrogen ions that acidify the urine. This process helps dissolve certain types of kidney stones or enhances the effect of some antibiotics.
• +Ginger root1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ginger belongs to the phytotherapeutic agents. The active components, such as gingerols and shogaols, act on the gastrointestinal tract by accelerating gastric emptying and blocking the 5-HT3 receptors in the vomiting center. This suppresses the feeling of nausea and normalizes digestion.

  Dosage: Usually 250 to 1000 mg per day, divided into multiple doses; do not exceed the daily amount of 2 grams.
• +Ginger allergenic extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This extract contains specific proteins from the ginger plant that can trigger an immune response in sensitive individuals. By applying a small amount in or on the skin, a doctor can observe whether a local inflammatory reaction occurs. This confirms whether the patient's immune system has produced antibodies against ginger allergens.
• +Chlorpheniramine / Phenylpropanolamine1 bronniet vrij verkrijgbaar — vraag je arts
• +Abatacept1 bronop voorschrift — vraag je arts
  About the substance

  Selective costimulation modulator that inhibits T-lymphocytes by binding to CD28 receptors on antigen-presenting cells, thereby blocking the full activation of T-cells.

  Dosage: Subcutaneous: 125 mg weekly. Intravenous: dosage depends on body weight, administered every four weeks after an initial loading phase.
• +Triprolidine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  First-generation histamine H1-antagonist that competitively blocks H1 receptors.
• +Ginger extract1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  The active substances in ginger, such as gingerols and shogaols, act on the gastrointestinal tract and the central nervous system. They have a direct effect on gastric motility and block the serotonin receptors in the intestines that send nausea signals to the brain. This helps to calm the stomach and suppress the urge to vomit.

  Dosage: Use according to the packaging, usually 250-500 mg per dose; maximum 2 grams per day.
• +Aspirin / Oxycodone1 bronniet vrij verkrijgbaar — vraag je arts
• +Aspirin / butalbital1 bronop voorschrift — vraag je arts
• +Nabilone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic cannabinoid that acts as a weak partial agonist at CB1 and CB2 receptors, mimicking the pharmacological activity of THC.

  Dosage: 2 to 3 times daily, starting 1 to 3 hours before chemotherapy and continued until 48 hours after the cycle.
• +Aspirin / Pentazocine1 bronniet vrij verkrijgbaar — vraag je arts
• +Aspirin / Caffeine / dihydrocodeine1 bronniet vrij verkrijgbaar — vraag je arts
• +Norgestrel1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Norgestrel binds to progesterone receptors in the body and inhibits the release of gonadotropins by the pituitary gland, which prevents ovulation. It also causes thickening of the cervical mucus, preventing sperm from reaching the uterus. This effectively minimizes the chance of fertilization and implantation.
• +Propofol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Intravenous anesthetic that induces sedation and anesthesia through positive modulation of the inhibitory function of the neurotransmitter GABA via GABA receptors.

  Dosage: Individually determined; induction in adults <55 years: 1.5–2.5 mg/kg i.v. (20–40 mg per 10 seconds). In elderly (>55 years) or ASA III/IV: reduction to at least 1 mg/kg.
• +Tannic Acid1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tannic acid is a plant-based tannin that causes proteins in the upper skin or mucous membrane layer to precipitate. This forms a protective layer that constricts blood vessels and stops the secretion of wound fluid. Through this astringent effect, the tissue is protected and can heal faster.

  Dosage: Apply locally to the affected area; do not swallow.
• +Tazarotene1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tazarotene is a prodrug from the acetylenic class of retinoids that, after conversion, regulates cell proliferation and differentiation.
• +Aspirin / Hydrocodone1 bronniet vrij verkrijgbaar — vraag je arts
• +Diphenhydramine / Ibuprofen1 bronniet vrij verkrijgbaar — vraag je arts
• +Phenyltoloxamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This agent is an antihistamine that blocks H1 receptors, counteracting the effects of histamine. Histamine is the substance responsible for allergic reactions such as itching and swelling. Additionally, it has a mild sedative effect, which, in combination with painkillers, can help improve rest and reduce pain perception.
• +Zanamivir1 bronop voorschrift — vraag je arts
  About the substance

  Zanamivir is a selective neuraminidase inhibitor that blocks the spread of the influenza virus by preventing new virus particles from being released from infected cells.

  Dosage: Treatment: 2 inhalations twice daily (total 10 mg) for 5 days. Prophylaxis: 2 inhalations once daily for 10 to 28 days. Always use the provided Diskhaler.
• +Aspirin / Meprobamate1 bronniet vrij verkrijgbaar — vraag je arts
• +Phenol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Antiseptic and disinfectant agent with local anesthetic properties; works by protein denaturation and cell membrane disruption in microorganisms and nociceptors.
• +Phenazopyridine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A urinary tract analgesic that acts as an azo dye and has a local anesthetic effect on the mucous membrane of the lower urinary tract.

  Dosage: 1 tablet 3 times a day after meals, for a maximum of 2 days.
• +Aspirin / Methocarbamol1 bronniet vrij verkrijgbaar — vraag je arts
• +Collagen1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Collagen is a structural protein that acts as a building block for connective tissue in the body. Upon ingestion, it is broken down in the gastrointestinal tract into amino acids and peptides, which are then absorbed into the bloodstream. These building blocks stimulate the body's own production of collagen in the dermis and joint tissues, contributing to the elasticity and structural integrity of these tissues.

  Dosage: The usual dosage varies between 2.5 and 10 grams per day, depending on the specific product type.
• +Celecoxib1 bronop voorschrift — vraag je arts
  About the substance

  Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor from the class of non-steroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the synthesis of prostaglandins via selective blockade of the COX-2 enzyme, leading to a reduction in pain and inflammation.

  Dosage: Osteoarthritis: 200 mg once daily or 100 mg twice daily. Rheumatoid arthritis and ankylosing spondylitis: 100 mg twice daily. If necessary, increase to 200 mg twice daily.
• +Magnesium salicylate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Magnesium salicylate belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and salicylates. It inhibits the production of prostaglandins by blocking the enzyme cyclooxygenase, which reduces pain signaling and the inflammatory response in the body. The addition of magnesium can help buffer the stomach acid-related side effects often associated with salicylates.

  Dosage: Usually 325 to 650 mg every 4 hours, with a maximum of 4 grams per 24 hours; take with a full glass of water.
• +Valacyclovir1 bronop voorschrift — vraag je arts
  About the substance

  Valaciclovir is a prodrug of acyclovir, belonging to the antiviral nucleoside analogues. In the body, it is converted into acyclovir, which is phosphorylated by viral enzymes into an active form that blocks viral DNA polymerase. As a result, the virus cannot copy its genetic material and viral replication stops.
• +Acetaminophen / Aspirin1 bronniet vrij verkrijgbaar — vraag je arts
• +Aspirin / Caffeine / salicylamide1 bronniet vrij verkrijgbaar — vraag je arts
• +Neomycin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to bacterial ribosomes, leading to cell death in susceptible gram-positive and gram-negative bacteria.

  Dosage: Cream and ointment: Apply to the skin 1 to 3 times daily.
• +L04AJ011 bronop voorschrift — vraag je arts
  About the substance

  This medication is a monoclonal antibody that specifically binds to immunoglobulin E (IgE). By lowering free IgE levels in the blood, it prevents IgE from binding to receptors on mast cells and basophils. This inhibits the release of inflammatory mediators such as histamine, thereby suppressing the symptoms of hives.
• +Codeine1 bronop voorschrift — vraag je arts
  About the substance

  A natural opium alkaloid and opioid analgesic that acts as a central antitussive by suppressing the cough center and as an antiperistaltic agent.

  Dosage: Adults: 10 mg every 4 to 6 hours (max. 120 mg/day). Children 12-18 years: 10 mg 4 times daily (max. 1 mg/kg/day). Oral use.
• +Diclofenac Potassium1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits the enzymes cyclooxygenase (COX)-1 and -2, thereby blocking the synthesis of prostaglandins (mediators of pain and inflammation).

  Dosage: For cataract surgery: 1 drop 4 times daily, starting 24 hours after surgery for 2 weeks. For refractive surgery: 1 hour before surgery, 15 minutes after surgery, then 4 times daily for a maximum of 3 days.
• +Clioquinol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Clioquinol is a halogenated hydroxyquinoline with antifungal and antiprotozoal properties, used both locally and systemically.

  Dosage: Topical: 2 to 4 times daily. Oral (adults): 250 mg 3 times daily for 10 days, with a lifetime cumulative limit of 10 grams.
• +Risedronate1 bronop voorschrift — vraag je arts
  About the substance

  Risedronate belongs to the class of bisphosphonates. It attaches to bone tissue and inhibits the activity of osteoclasts, the cells that break down bone tissue. This slows down bone resorption while bone formation by osteoblasts continues, leading to higher bone density and stronger bones.
• +Tiotropium1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tiotropium is a long-acting anticholinergic (LAMA). It blocks the muscarinic receptors (M3 receptors) in the smooth muscles of the airways, counteracting the effect of acetylcholine. This leads to long-lasting relaxation of the airways (bronchodilation), which facilitates breathing.
• +Diclofenac1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits the enzymes cyclooxygenase (COX)-1 and -2, thereby blocking the synthesis of prostaglandins (mediators of pain and inflammation).

  Dosage: For cataract surgery: 1 drop 4 times daily, starting 24 hours after surgery for 2 weeks. For refractive surgery: 1 hour before surgery, 15 minutes after surgery, then 4 times daily for a maximum of 3 days.
• +Etomidate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Imidazole derivative that acts as a short-acting hypnotic for the induction of general anesthesia.

  Dosage: 0.3 mg/kg body weight (intravenous), maximum 3 ampoules (30 ml).
• +Acyclovir1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Acyclovir is an antiviral agent that specifically interferes with the replication of herpes viruses. It is converted by viral enzymes into an active form that disrupts viral DNA synthesis by incorporating itself into the DNA chain. This stops the growth and spread of the virus in the infected skin cells.

  Dosage: Apply the cream to the affected area 5 times a day for 4 to 10 days.
• +Histamine1 bronop voorschrift — vraag je arts
  About the substance

  Histamine is an endogenous substance that acts as a neurotransmitter and inflammatory mediator. In this context, it stimulates parietal cells in the stomach wall via H2 receptors to secrete gastric acid. This is used to test the secretory capacity of the stomach.
• +Maprotiline1 bronop voorschrift — vraag je arts
  About the substance

  Tetracyclic antidepressant that inhibits the neuronal reuptake of noradrenaline and possesses anticholinergic properties.

  Dosage: Adults: 25 mg 1-3 times daily or 75 mg once daily in the evening; maintenance dosage 75-150 mg/day. Elderly: 25 mg once daily in the evening, gradually increase.
• +Brompheniramine / Phenylpropanolamine1 bronniet vrij verkrijgbaar — vraag je arts
• +RimabotulinumtoxinB1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  RimabotulinumtoxinB is a neurotoxin that blocks the release of acetylcholine at nerve endings. It cleaves specific proteins (SNARE complex) required for the fusion of vesicles with the cell membrane. This interrupts nerve impulse transmission to the muscle, leading to muscle relaxation.
• +Dexchlorpheniramine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A potent antihistamine (S-enantiomer of chlorpheniramine) that blocks histamine signaling through competitive inhibition of H1 receptors, combined with anticholinergic and sedative properties.
• +Urtica preparation1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Nettle preparations contain various active substances such as flavonoids and acids that have anti-inflammatory and diuretic properties. They influence the excretion of fluid via the kidneys and can slightly inhibit the production of pro-inflammatory substances in the body. The exact pharmacological action is complex due to the combination of different plant components.

  Dosage: Follow the instructions on the packaging, as the concentration can vary significantly per preparation.
• +Flurbiprofen1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A propionic acid derivative NSAID that inhibits pain, fever, and inflammation by blocking prostaglandin synthesis via mixed COX-1/COX-2 inhibition.

  Dosage: Sore throat (adults/children >12y): 8.75 mg every 3-6 hours, maximum 5 lozenges per 24 hours, for a maximum of 3 days.
• +Carbinoxamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  First-generation antihistamine that acts as a competitive antagonist at the H1 receptor, blocking the effects of histamine.
• +Hyaluronan1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Hyaluronic acid is a naturally occurring polysaccharide that can bind large amounts of water. In the eye, it forms a viscoelastic layer that protects and hydrates the eye surface by stabilizing the tear film. It acts as a lubricant that reduces friction and supports the recovery of the epithelium.

  Dosage: As needed, 1 drop in the affected eye 1 or more times per day.
• +Aspirin / Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Baclofen1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Baclofen is a GABA-β receptor agonist that acts as a centrally acting spasmolytic. By stimulating these receptors in the spinal cord, it suppresses mono- and polysynaptic reflex transmission, leading to muscle relaxation.

  Dosage: The dosage is strictly individual and requires titration; for intrathecal administration, a test phase via bolus injection is started, followed by continuous infusion via an implantable pump.
• +Sulfamethoxazole / Trimethoprim1 bronop voorschrift — vraag je arts
• +Lactate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Lactate acts as a buffer that maintains the natural acidic pH value of the vagina. A low pH is crucial for maintaining vaginal flora, as it makes colonization by pathogenic microorganisms more difficult. It supports physiological balance by making the environment unfavorable for infectious agents.

  Dosage: Use according to the package leaflet of the specific product, usually as a vaginal gel or ovule.
• +Desipramine1 bronop voorschrift — vraag je arts
  About the substance

  Tricyclic antidepressant (TCA) that potently inhibits the reuptake of norepinephrine. It works by blocking histamine H1, alpha-1-adrenergic, and muscarinic receptors.

  Dosage: Tablets, to be taken one or more times per day with or without food at a fixed time.
• +Sumatriptan1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Selective 5-HT1 receptor agonist that causes vasoconstriction in cranial blood vessels through activation of vascular 5-HT1 receptors.

  Dosage: Do not use prophylactically. For migraine: as soon as possible after the start of the headache. Maximum 200 mg (tablets) or 40 mg (nasal spray) per 24 hours. A second dose can be taken after at least 2 hours.
• +HYLAN G-F 201 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Hylan G-F 20 is a viscoelastic fluid based on hyaluronic acid that is injected into the joint. It restores the viscoelasticity of the synovial fluid, allowing the joint to be better lubricated and shocks to be absorbed more effectively. This reduces friction between the cartilage surfaces and relieves pain.
• +Aspirin / Chlorpheniramine / Phenylephrine1 bronniet vrij verkrijgbaar — vraag je arts
• +Creosote1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A mixture of phenols (including cresols) and polycyclic aromatic hydrocarbons, formerly used as a disinfectant, laxative, and dermatological agent.
• +Zoledronic acid1 bronop voorschrift — vraag je arts
  About the substance

  Zoledronic acid is a potent bisphosphonate that binds strongly to bone mineral. It blocks the action of osteoclasts, the cells that break down bone tissue, and induces their cell death. This strongly inhibits bone resorption, which strengthens bone structure and lowers the risk of fractures.
• +Acetaminophen / Aspirin / Caffeine / salicylamide1 bronniet vrij verkrijgbaar — vraag je arts
• +Salicylamide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Salicylamide is a derivative of salicylic acid with analgesic and antipyretic properties. It works by inhibiting the synthesis of prostaglandins in the central nervous system. It is often combined with other substances to enhance the analgesic effect.
• +Triamcinolone Acetonide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Triamcinolone is a synthetic corticosteroid that exerts anti-inflammatory and immunosuppressive effects by binding to glucocorticoid receptors, leading to modulation of gene expression and suppression of the immune response.

  Dosage: For inhalation: 3 to 4 times daily at regular intervals. For injections (10-40 mg/ml) and dermatological applications, the dosage varies significantly depending on the indication and form of administration.
• +Pheniramine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  First-generation antihistamine of the alkylamine class that acts as an H1 receptor antagonist.
• +Belladonna Alkaloids1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Belladonna alkaloids (such as atropine and scopolamine) are anticholinergics that block the action of acetylcholine. They inhibit parasympathetic nerve activity, leading to relaxation of smooth muscles in organs and a reduction in glandular secretions. This effect helps in reducing spasms and cramps.
• +Naloxone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Naloxone is a competitive opioid antagonist with high affinity for μ-opioid receptors, where it acts as an inverse agonist to displace and block the effects of opioids.

  Dosage: Available as nasal spray, intramuscular, intravenous, or subcutaneous injection for emergency therapy; dosage depends on the clinical situation and route of administration.
• +Sodium Oxybate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  It is a central nervous system depressant closely related to the neurotransmitter GABA. It influences sleep architecture by consolidating deep sleep phases and stabilizing the sleep-wake cycle, which leads to better sleep at night and fewer unexpected daytime sleep attacks.
• +Leflunomide1 bronop voorschrift — vraag je arts
  About the substance

  Leflunomide is a disease-modifying antirheumatic drug (DMARD) that acts as an inhibitor of pyrimidine synthesis, leading to an antiproliferative and immunosuppressive effect on activated lymphocytes.

  Dosage: Usually once daily; the doctor may prescribe a higher starting dose for the first three days.
• +Aspirin / Chlorpheniramine / Dextromethorphan / Phenylephrin1 bronniet vrij verkrijgbaar — vraag je arts
• +Ciclopirox1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ciclopirox is a synthetic antifungal (pyridone derivative) with fungicidal, fungistatic, and sporicidal properties. It works by disrupting the cell metabolism of fungi, leading to the death of the fungal cell.

  Dosage: Nail lacquer: apply a thin layer once daily to the affected nail(s) and adjacent skin. Cream: apply twice daily for 2-4 weeks.
• +Goserelin1 bronop voorschrift — vraag je arts
  About the substance

  Synthetic LHRH analogue (LHRH agonist) that inhibits LH secretion by the pituitary gland through chronic stimulation, resulting in a decrease of testosterone in men and estradiol in women to castration levels.

  Dosage: Subcutaneous injection (depot); frequency and dose depend on the specific indication and product form (ZOLADEX or ZOLADEX Long Acting), to be administered in the anterior abdominal wall.
• +Etanercept1 bronop voorschrift — vraag je arts
  About the substance

  A dimeric fusion protein that acts as a TNF-α inhibitor by binding to tumor necrosis factor (TNF), thereby neutralizing the biological activity of this pro-inflammatory cytokine.

  Dosage: 50 mg once weekly subcutaneously; for plaque psoriasis, 50 mg may be administered twice weekly for the first 3 months.
• +Bacitracin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Bacitracin is a polypeptide antibiotic for topical use that inhibits bacterial cell wall synthesis by interfering with the dephosphorylation of the lipid pyrophosphate transport molecule.

  Dosage: Apply a thin layer of ointment to the cleaned wound twice daily; maximum treatment duration 8 days.
• +Oxytocin1 bronop voorschrift — vraag je arts
  About the substance

  A synthetic nonapeptide that acts as an agonist at G-protein-coupled oxytocin receptors in the myometrium, leading to contraction of the smooth muscles of the uterus.

  Dosage: Intravenous drip infusion or via infusion pump: add 5 I.U. to 500 ml of physiological saline (0.9% NaCl) or 5% glucose solution.
• +Trazodone1 bronop voorschrift — vraag je arts
  About the substance

  Trazodone is an antidepressant from the SARI class (serotonin antagonist and reuptake inhibitor) that inhibits serotonin reuptake and blocks postsynaptic 5HT2A receptors.

  Dosage: Starting dose 150 mg per day, in divided doses after meals or as a single dose before bedtime; increase by 50 mg every 3-4 days up to a maximum of 400 mg per day.
• +Brompheniramine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A histamine H1-antagonist that blocks the effects of histamine; it also exhibits anticholinergic properties.

  Dosage: Chewable tablets and liquid: every 4 to 6 hours; extended-release tablets/capsules: every 8 or 12 hours.
• +Rofecoxib1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Selective COX-2 inhibitor (prostaglandin G/H synthase 2 inhibitor) that inhibits the synthesis of prostaglandins.

  Dosage: Oral doses of 12.5 mg, 25 mg, and 50 mg.
• +Naltrexone1 bronop voorschrift — vraag je arts
  About the substance

  Naltrexone is a specific opioid antagonist that binds competitively to opioid receptors in the central and peripheral nervous system, blocking access for exogenous opioids.

  Dosage: Starting dose 25 mg, followed by a usual dose of 50 mg (one tablet) per day.
• +Nicotine1 bronop voorschrift — vraag je arts
  About the substance

  Nicotine is an agonist of nicotinic cholinergic receptors in the central and peripheral nervous system, leading to stimulation of neurons and ultimately blockade of synaptic transmission.

  Dosage: Depends on the dosage form (patches, lozenges, nasal spray) and the degree of dependence; must be determined individually.
• +Polymyxin B1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Polymyxin B is an antibiotic that damages the cell membrane of gram-negative bacteria. It acts as a detergent that binds to the phospholipids in the membrane, increasing permeability and causing the cell contents to leak. This leads to the death of the bacteria.
• +Mercaptopurine1 bronop voorschrift — vraag je arts
  About the substance

  Mercaptopurine is a cytotoxic antimetabolite and purine analogue that, after intracellular conversion to thioguanine nucleotides, inhibits de novo purine synthesis and is incorporated into nucleic acids, leading to cell death.

  Dosage: The usual dose is 2.5 mg/kg per day, strictly adjusted based on hematotoxicity and the treatment protocol; preferably taken in the evening, consistently with or without food, but at least 1 hour before or 2 hours after dairy products.
• +Urea1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Urea is a keratolytic agent that binds water in the stratum corneum of the skin (humectant). It breaks the hydrogen bonds in keratin proteins, making it easier for dead skin cells to shed and hydrating the skin barrier. This process softens the skin and improves the absorption of other nourishing ingredients.
• +Pamidronate1 bronop voorschrift — vraag je arts
  About the substance

  This medication belongs to the class of bisphosphonates. It attaches to bone tissue and inhibits the activity of osteoclasts, the cells responsible for bone breakdown. This slows down bone resorption and normalizes calcium levels in the blood, which reduces bone pain and lowers the risk of fractures.
• +Sulindac1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class; it is a prodrug that inhibits prostaglandin synthesis by inhibiting COX-1 and COX-2.

  Dosage: Take twice daily with food at fixed times.
• +Gemfibrozil1 bronop voorschrift — vraag je arts
  About the substance

  Gemfibrozil is a fibric acid derivative (fibrate) that regulates lipid metabolism by activating the PPAR-alpha receptor, leading to increased lipolysis and decreased synthesis of triglycerides and VLDL.

  Dosage: 600 mg twice daily, half an hour before breakfast and half an hour before dinner. In cases of mild to moderate renal impairment, start with 900 mg/day.
• +Mitoxantrone1 bronop voorschrift — vraag je arts
  About the substance

  A DNA-reactive anthracenedione-derived antineoplastic substance that acts as a potent inhibitor of topoisomerase II and causes DNA crosslinking, leading to cell death in both proliferating and non-proliferating cells.

  Dosage: For breast cancer and non-Hodgkin lymphoma: 14 mg/m² intravenously, every 21 days (lower dose for reduced bone marrow reserve). For MS: usually once every three months. For prostate cancer: once every 21 days.
• +Sulfasalazine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  An azo compound that breaks down in the intestine into 5-aminosalicylic acid (mesalazine) and sulfapyridine; it acts as a DMARD and anti-inflammatory agent with immunosuppressive properties.

  Dosage: Adults: 2-6 g daily (bowel diseases) or 2-3 g daily (rheumatoid arthritis), divided into several intakes during meals.
• +Simethicone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Simethicone is an inert surface-active agent (antifoaming agent). It lowers the surface tension of gas bubbles in the gastrointestinal tract, causing them to merge into larger bubbles that can be more easily expelled by the body. It is not absorbed into the blood.

  Dosage: Take after meals or at bedtime; maximum 500 mg per day.
• +Aspirin / Citric Acid / Sodium Bicarbonate1 bronniet vrij verkrijgbaar — vraag je arts
• +Acetaminophen / Aspirin / Caffeine1 bronniet vrij verkrijgbaar — vraag je arts
• +Clemastine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  First-generation histamine H1-antagonist with pronounced anticholinergic and sedative properties.

  Dosage: Adults and children > 12 years: 1 mg orally twice daily. For anaphylaxis/angioedema: 2 mg i.v. or i.m. twice daily.
• +Carisoprodol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant that suppresses neuronal communication in the reticular formation and the spinal cord.

  Dosage: Three times daily and at bedtime.
• +Verapamil1 bronop voorschrift — vraag je arts
  About the substance

  Verapamil is a non-dihydropyridine calcium antagonist (phenylalkylamine) that inhibits calcium influx through slow channels in the cell membrane, leading to reduced contractility and conduction in the heart and vasodilation.

  Dosage: 120 to 480 mg per day, divided into 2 to 4 doses per day.
• +Imipramine1 bronop voorschrift — vraag je arts
  About the substance

  Imipramine is a tricyclic antidepressant (TCA) that inhibits the neuronal reuptake of norepinephrine and serotonin. Additionally, it blocks muscarinic, histamine H1, and alpha-1 adrenergic receptors.

  Dosage: Depression: 1 or more times per day, with or without food. Nocturnal enuresis: 1 hour before bedtime (optionally supplemented with a dose in the afternoon).
• +Doxepin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Psychotropic agent, closely related to tricyclic antidepressants, with antidepressant, anxiolytic, and sedative properties.

  Dosage: Topical cream: Apply 4 times daily with at least 3-4 hours between applications, for a maximum of 8 days.
• +Isosorbide1 bronop voorschrift — vraag je arts
  About the substance

  This agent belongs to the group of nitrates. It is converted in the body into nitric oxide, a substance that relaxes the smooth muscles in blood vessel walls. This causes the blood vessels to dilate, which improves blood flow to the heart and reduces the workload on the heart, thereby decreasing the oxygen demand of the heart muscle.
• +Tamsulosin1 bronop voorschrift — vraag je arts
  About the substance

  Tamsulosin is a selective alpha-1-adrenoceptor antagonist that causes relaxation of smooth muscle tissue by competitively binding to alpha-1A and alpha-1D receptors in the prostate and urethra.

  Dosage: 1 tablet of 0.4 mg once daily, to be swallowed whole without chewing or crushing, with or without food.
• +Hyaluronate1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Hyaluronic acid is a substance produced by the body that acts as a natural lubricant and moisture binder. In the eye, it forms a stable, protective layer on the cornea that retains moisture for a long time. In joints, it helps maintain the viscosity of the synovial fluid, which ensures better shock absorption and smoother movement.

  Dosage: For dry eyes: 1 drop in the affected eye, as often as needed. Do not use if the packaging is damaged.
• +Imiquimod1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Imiquimod is an immune response modifier and Toll-like receptor 7 (TLR-7) agonist that stimulates the local immune response through the induction of alpha-interferon and other cytokines.

  Dosage: Genital warts: 3x per week (leave on for 6-10 hours); Actinic keratosis: 2x per week (leave on for approx. 8 hours); Superficial basal cell carcinoma: 5x per week (leave on for approx. 8 hours). Always apply before bedtime.
• +Chlorpromazine1 bronop voorschrift — vraag je arts
  About the substance

  A phenothiazine antipsychotic that acts as a dopamine D2-receptor antagonist; the therapeutic effect is based on the brain's long-term adaptation to this blockade.

  Dosage: Usually 2 to 4 times daily. For nausea/vomiting every 4-6 hours as needed; for pre-operative nervousness 2-3 hours before surgery; for hiccups a maximum of 3 days.
• +Indomethacin1 bronop voorschrift — vraag je arts
  About the substance

  Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) that works through potent, non-selective inhibition of the enzyme cyclooxygenase (COX), thereby blocking the synthesis of prostaglandins and thromboxane.

  Dosage: Capsules/suspension: 2-4x daily; extended-release capsules: 1-2x daily; suppositories: 2-4x daily. Preferably taken with food or antacids.
• +Leuprolide1 bronop voorschrift — vraag je arts
  About the substance

  This medication is a GnRH agonist that regulates the natural production of sex hormones. With continuous administration, it causes the receptors in the pituitary gland to become desensitized, which strongly suppresses the production of testosterone or estrogen in the gonads. This process halts the hormonal stimulation of the condition.
• +Meprobamate1 bronop voorschrift — vraag je arts
  About the substance

  A carbamate derivative with hypnotic, anxiolytic, and muscle-relaxant properties that acts as a central nervous system depressant.

  Dosage: Take 2 to 4 times per day as a tablet or extended-release capsule.
• +Gabapentin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Gabapentin is an antiepileptic drug that binds to the α2δ subunit of voltage-gated calcium channels in the central nervous system, thereby modulating neurotransmission.

  Dosage: Starting schedule for adults/adolescents (≥12 years): day 1: 300 mg once daily, day 2: 300 mg twice daily, day 3: 300 mg three times daily. Discontinue by gradually tapering over at least 1 week.
• +Allopurinol1 bronop voorschrift — vraag je arts
  About the substance

  Allopurinol is a xanthine oxidase inhibitor that lowers uric acid production by blocking the oxidation of hypoxanthine and xanthine into uric acid.

  Dosage: Starting dose 100 mg per day, maintenance dose 100-900 mg per day depending on severity; pediatric 2-10 mg/kg of body weight/day.
• +Orphenadrine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This agent acts as a centrally acting muscle relaxant with anticholinergic properties. It blocks the action of acetylcholine in the central nervous system, which reduces muscle tension. Additionally, it has a mild analgesic effect due to its influence on pain perception in the brain.
• +Pentoxifylline1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A xanthine derivative and peripheral vasodilator that lowers blood viscosity by improving erythrocyte deformability and lowering fibrinogen levels.

  Dosage: 2 to 3 tablets per day, to be taken during or after a meal with half a glass of liquid; in case of severe kidney or liver function impairment, reduce the dose by 30 to 50%.
• +Lidocaine1 bronop voorschrift — vraag je arts
  About the substance

  Lidocaine is a class IB antiarrhythmic and local anesthetic that blocks sodium channels, thereby stabilizing the membrane, reducing automaticity in the heart, and suppressing conduction in nerve tissue.

  Dosage: Individual dosage under ECG monitoring; in case of shock, heart failure, or liver failure, significantly reduce the dose.
• +Capsaicin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Highly selective agonist for the TRPV1 receptor (transient receptor potential vanilloid 1). The mechanism relies on initial activation of nociceptors followed by desensitization, making them less sensitive to stimuli.

  Dosage: Apply a maximum of 4 patches to intact, dry skin by a healthcare professional; application time 30 minutes for the feet and 60 minutes for other body parts.
• +Tranexamic Acid1 bronop voorschrift — vraag je arts
  About the substance

  It belongs to the class of antifibrinolytics. It blocks the binding of plasminogen to fibrin, thereby inhibiting the breakdown of blood clots (fibrinolysis). This keeps a formed clot intact for longer, which helps to effectively stop bleeding.
• +Misoprostol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic prostaglandin E1 analog (mucosal protectant) that inhibits gastric acid secretion via direct action on parietal cells and increases uterine tone by stimulating prostaglandin receptors.

  Dosage: Gastric ulcers: 200 micrograms four times daily. Duodenal ulcers: 800 micrograms per day (divided into 2 or 4 doses). NSAID-related ulcers: 400-800 micrograms per day (divided into 2 or 4 doses). Take with meals and at bedtime.
• +Adalimumab1 bronop voorschrift — vraag je arts
  About the substance

  A TNF-alpha inhibitor (monoclonal antibody) that specifically binds to TNF and blocks its interaction with p55 and p75 receptors, thereby modulating inflammatory processes and leukocyte migration.

  Dosage: Subcutaneous injection, usually once every two weeks; for specific indications such as rheumatoid arthritis or Crohn's disease, different frequencies may apply.
• +Oxymetazoline1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha-adrenergic agonist with affinity for both alpha-1 and alpha-2 adrenoceptors.

  Dosage: Adults and children >10 years: 1-2 sprays per nostril, maximum 2-3 times daily. Children 6-10 years: 1 spray per nostril, maximum 2-3 times daily. Use for a maximum of 7 consecutive days.
• +Infliximab1 bronop voorschrift — vraag je arts
  About the substance

  Chimeric human-murine monoclonal antibody that acts as a TNF-alpha inhibitor by binding with high affinity to both soluble and transmembrane forms of TNF-alpha.

  Dosage: Intravenous infusion; dosage and frequency depend on the indication, to be administered exclusively by qualified medical personnel.
• +Nortriptyline1 bronop voorschrift — vraag je arts
  About the substance

  Tricyclic antidepressant (TCA) with thymoanaleptic and psychostimulant properties. It works primarily by inhibiting the reuptake of neurotransmitters in the synaptic cleft, which improves mood.

  Dosage: Starting dose 50 mg/day (or 25 mg 2-3 times daily), gradually increase. Doses above 150 mg/day preferably in a clinical setting (max. 200-250 mg/day).
• +Metoclopramide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Metoclopramide is a dopamine D2 antagonist and substituted benzamide with prokinetic properties. It increases gastric emptying and intestinal transit by stimulating antral contractions and relaxing the pyloric sphincter.

  Dosage: Adults: 10 mg per dose, maximum 30 mg or 0.5 mg/kg per day. Intravenous administration as a slow bolus over at least 3 minutes.
• +Pioglitazone1 bronop voorschrift — vraag je arts
  About the substance

  Thiazolidinedione (TZD) that acts as an agonist on the PPARγ receptor; this increases insulin sensitivity in the liver, adipose tissue, and muscle tissue, thereby decreasing hepatic glucose output and increasing peripheral glucose uptake.

  Dosage: Starting dose 15 mg or 30 mg once daily; increase in steps to a maximum of 45 mg once daily.
• +Phenytoin1 bronop voorschrift — vraag je arts
  About the substance

  Phenytoin is an antiepileptic from the hydantoin derivative class. It works via voltage-dependent blocking of sodium channels, suppressing high-frequency neuronal discharges.

  Dosage: Adjust individually based on serum levels (target value 10-20 µg/ml). Start with a low dose and increase gradually at intervals of 7 to 10 days.
• +Tacrolimus1 bronop voorschrift — vraag je arts
  About the substance

  Immunosuppressant from the macrolide class; it inhibits calcineurin by binding to the immunophilin FKBP12, thereby blocking calcium-dependent signal transduction and the production of pro-inflammatory cytokines (such as IL-2) in T-cells.

  Dosage: Topical: apply twice daily to the affected skin until healed, then intermittently for maintenance; systemic: individually determined via continuous infusion or oral administration.
• +Esomeprazole1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Esomeprazole is a proton pump inhibitor (PPI) that inhibits gastric acid secretion by binding covalently to the H+, K+-ATPase enzyme (the proton pump) in the parietal cell.

  Dosage: Erosive reflux esophagitis: 40 mg once daily. Symptomatic GERD or long-term treatment: 20 mg once daily.
• +Hydroxyurea1 bronop voorschrift — vraag je arts
  About the substance

  This agent is an antimetabolite that inhibits the enzyme ribonucleotide reductase. This enzyme is essential for the synthesis of DNA in rapidly dividing cells. By disrupting DNA production, uncontrolled cell division is inhibited, and in sickle cell anemia, it stimulates the production of fetal hemoglobin, which reduces symptoms.
• +Dactinomycin1 bronop voorschrift — vraag je arts
  About the substance

  Antineoplastic antibiotic that binds to DNA and inhibits RNA synthesis (transcription), thereby blocking protein synthesis in rapidly dividing cells.
• +Citric Acid1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Citric acid acts as an organic acid that can influence the pH of urine. By making the urine less acidic, it hinders the formation of certain types of kidney stones, such as calcium oxalate stones. It works by binding calcium ions, making them less likely to precipitate as crystals.

  Dosage: Always follow the doctor's specific prescription, as the dosage depends heavily on the desired urinary pH.
• +Ranitidine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Histamine H2-receptor antagonist that inhibits gastric acid secretion by competitively blocking H2 receptors on the parietal cells in the stomach.

  Dosage: Usually once daily before bedtime or 2-4 times daily; for prevention, 30-60 minutes before consuming food or drink.
• +Nystatin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Nystatin is a polyene antibiotic with fungicidal activity. It binds to sterols in the fungal cell membrane, increasing membrane permeability and causing the loss of intracellular material.

  Dosage: Adults: 4-6 ml (400,000-600,000 IU) 4 times daily. Newborns: 1 ml (100,000 IU) 4 times daily. Infants: 2 ml (200,000 IU) 4 times daily. Administration: apply in the mouth.
• +Nifedipine1 bronop voorschrift — vraag je arts
  About the substance

  Dihydropyridine calcium antagonist that inhibits the influx of calcium ions into myocardial cells and vascular smooth muscle cells. This leads to relaxation of smooth muscle cells (vasodilation) and a reduction in myocardial oxygen demand.

  Dosage: Starting dose 30 mg once daily (extended-release tablets), to be increased in steps to a maximum of 120 mg once daily.
• +Budesonide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A non-halogenated glucocorticosteroid that binds to the glucocorticoid receptor to inhibit the expression of pro-inflammatory signaling molecules, thereby reducing inflammatory infiltrates.

  Dosage: For EoE in children (2-11 years): 1 mg per day, divided into 0.5 mg in the morning and 0.5 mg in the evening. For adults: see doctor's prescription; swallow capsules whole, preferably once daily in the morning.
• +Heparin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Antithrombotic agent of the heparin group that binds to antithrombin III, accelerating the inactivation of thrombin and clotting factors (Xa, IX, XI, XIII) and inhibiting platelet aggregation.

  Dosage: No standard dosage; the dosage is subject to interindividual variations and must be carefully adjusted based on body weight, clinical examination, and lab tests (APTT or ACT) to achieve an optimal effect without bleeding risk.
• +Racepinephrine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Racepinephrine is a mixture of epinephrine isomers that acts as a potent sympathomimetic. It stimulates alpha-adrenergic receptors in the airways, leading to direct vasoconstriction of the mucous membranes. This reduces airway swelling and improves breathing.
• +Cimetidine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Cimetidine is a histamine H2-receptor antagonist that inhibits gastric acid secretion, pepsin, and gastrin production through competitive blockade of the H2-receptor. Additionally, it non-specifically inhibits various cytochrome P450 enzymes (e.g., CYP1A2, CYP2D6, CYP3A4).

  Dosage: Adults (peptic ulcer): 800 mg at bedtime, or 400 mg twice daily (breakfast/bedtime), or 200 mg 3 times daily during meals plus 400 mg at bedtime.
• +Azathioprine1 bronop voorschrift — vraag je arts
  About the substance

  Azathioprine is a prodrug of 6-mercaptopurine, a purine antagonist that inhibits de novo purine synthesis and is incorporated into nucleic acids, leading to immunosuppression.

  Dosage: Transplantation: starting dose max 5 mg/kg/day, maintenance dose 1-4 mg/kg/day. Other conditions: starting dose 1-3 mg/kg/day.
• +Menthol1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Menthol activates the TRPM8 receptors in the skin, which normally respond to cold stimuli. This activation creates a cooling sensation on the skin, which masks pain perception and can locally dilate blood vessels. This results in an analgesic and refreshing effect on the treated area.
• +Phenobarbital1 bronop voorschrift — vraag je arts
  About the substance

  Barbiturate that acts as a non-selective central nervous system depressant. It works by binding to GABA receptors, keeping chloride ion channels open longer, which leads to hyperpolarization of the neuronal membrane and inhibition of nerve impulses.

  Dosage: Starting dose 2-3 mg/kg/day; usual maintenance dose 100-200 mg/day, to be taken as a single evening dose or divided into two doses.
• +Doxylamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Doxylamine is a histamine H1-antagonist with pronounced sedative properties. By blocking H1-receptors in the central nervous system and through anticholinergic effects, it influences the sleep-wake cycle and reduces nausea.

  Dosage: For insomnia: 30 minutes before bedtime. For cold symptoms: every 4 to 6 hours. Strictly follow the label or doctor's prescription.
• +Thyroid (USP)1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This medication contains the natural thyroid hormones T3 and T4. These hormones regulate metabolism in almost all body cells by increasing the rate of energy consumption and protein synthesis, thereby eliminating symptoms of a deficiency, such as fatigue and sensitivity to cold.
• +Cocaine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Stimulant that blocks the reuptake of neurotransmitters such as dopamine, noradrenaline, and serotonin, leading to an increased concentration of these substances in the synaptic cleft.
• +Pramoxine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Local anesthetic and antipruritic that blocks neuronal depolarization by preventing ionic fluctuations across the cell membrane, thereby suppressing the propagation of action potentials.

  Dosage: Cream/lozenges: maximum 5 times per day; spray/gel: 3 to 4 times per day. Use for a maximum of 7 days without medical advice.
• +Promethazine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Promethazine is a phenothiazine derivative that acts as an antagonist on various receptors, including histamine H1 receptors, muscarinic acetylcholine receptors, and dopamine D2 receptors.

  Dosage: Adults (allergy): 15-150 mg per day in divided doses during meals and at bedtime. Motion sickness (adults/children >8 years): 25 mg, 0.5-1 hour before departure, repeat after 8 hours if necessary. Children >2 years (allergy): 0.2 mg/kg 2-4 times per day.
• +Topiramate1 bronop voorschrift — vraag je arts
  About the substance

  Sulfamate-substituted monosaccharide with anti-epileptic and migraine-preventive effects. Its mechanism of action involves blocking voltage-gated sodium channels, which suppresses repetitive action potentials during sustained depolarization.

  Dosage: Start with a low dose and titrate based on clinical response; usually taken twice daily (morning and evening) with or without food.
• +Dopamine1 bronop voorschrift — vraag je arts
  About the substance

  Dopamine is a catecholamine neurotransmitter and sympathomimetic that acts via dopaminergic and adrenergic receptors to regulate hemodynamics.

  Dosage: Exclusively via continuous intravenous infusion into a large vein, dosage varying from 1 to 20 micrograms/kg/min depending on the desired effect.
• +Salicylic acid1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Keratolytic, bacteriostatic, and fungicidal agent that dissolves intercellular connections in the epidermis, causing the horny layer to shed.

  Dosage: Depending on the condition and the product; follow the instructions on the label or the doctor's prescription strictly.
• +Carbamazepine1 bronop voorschrift — vraag je arts
  About the substance

  Anticonvulsant and analgesic of the dibenzoazepine class that stabilizes excessive excitation of nerve membranes by blocking voltage-dependent sodium ion channels, thereby inhibiting repetitive neuronal discharges.

  Dosage: Regular tablets, chewable tablets, and suspension: 2-4 times daily with meals. Extended-release tablets: twice daily with meals. Extended-release capsules: twice daily with or without food. The dose should be built up individually and gradually.
• +OspA protein1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  The OspA protein is a surface protein of the Borrelia burgdorferi bacterium. When this protein is administered as a vaccine, the immune system recognizes it as foreign and produces specific antibodies. Upon a tick bite, these antibodies are ingested by the tick, where they neutralize the bacterium before it can be transmitted to humans.
• +Benzoyl Peroxide1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Anti-acne medication for topical use with an oxidizing mechanism of action; it breaks the peroxide bond, creating radicals that kill bacteria and reduce keratin/sebum.

  Dosage: Apply to cleaned skin 1 to 2 times daily; at the start of treatment, it is often started with 1 time daily.
• +Duloxetine1 bronop voorschrift — vraag je arts
  About the substance

  Duloxetine is a combined serotonin (5-HT) and norepinephrine (NA) reuptake inhibitor. By increasing extracellular levels of these neurotransmitters in the central nervous system, it normalizes pain thresholds and influences mood.

  Dosage: 60 mg once daily, to be taken with or without food.
• +Famotidine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Famotidine is a competitive histamine-2 (H2)-receptor antagonist that inhibits gastric acid secretion through selective blockade of H2 receptors on parietal cells in the stomach.

  Dosage: Ulcers: 40 mg at night (maintenance 20 mg at night). Reflux esophagitis: 20-40 mg twice daily. Zollinger-Ellison: starting dose 20 mg every 6 hours (max 800 mg/day). In case of severe renal impairment (creatinine clearance < 30 ml/min), halve the dosage.
• +Venlafaxine1 bronop voorschrift — vraag je arts
  About the substance

  Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that enhances neurotransmission in the central nervous system by blocking the reuptake of serotonin and norepinephrine, with slight inhibition of dopamine reuptake.

  Dosage: Starting dose 75 mg once daily (extended release), with a maximum of 375 mg per day; dose increases preferably at intervals of 2 weeks or more.
• +Niacin1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Niacin is a water-soluble vitamin that is converted in the body into the coenzymes NAD and NADP. These coenzymes are essential for hundreds of enzymatic reactions, including energy production from carbohydrates, fats, and proteins. It thereby supports metabolism and the functioning of the nervous system.
• +Clonazepam1 bronop voorschrift — vraag je arts
  About the substance

  Benzodiazepine with anxiolytic, hypnotic-sedative, muscle-relaxant, and anticonvulsant properties; works via positive allosteric modulation of the GABA-A receptor, enhancing inhibitory GABAergic neurotransmission and chloride ion flux.

  Dosage: To be adjusted individually by the physician; often start with a low dose that is gradually increased. Tablets are divisible for dose adjustment.
• +Phenylpropanolamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Sympathomimetic agent that acts as a non-selective adrenergic receptor agonist and norepinephrine reuptake inhibitor.
• +Rituximab1 bronop voorschrift — vraag je arts
  About the substance

  A genetically engineered chimeric monoclonal antibody (IgG1-kappa) that specifically binds to the CD20 antigen on B-lymphocytes, leading to B-cell depletion via immune-mediated mechanisms.

  Dosage: Subcutaneous formulation: fixed dose under close supervision; mandatory premedication with an antipyretic and antihistamine before each administration.
• +Hydrochlorothiazide1 bronop voorschrift — vraag je arts
  About the substance

  Thiazide diuretic that inhibits the reabsorption of sodium and chloride in the distal tubule of the kidney, leading to increased excretion of water and electrolytes.

  Dosage: Tablet or liquid, 1-2 times daily with a meal or snack; if taken once daily, take in the morning; if taken twice daily, take in the morning and late afternoon.
• +Pseudoephedrine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  This medication is a sympathomimetic that acts directly on the alpha-adrenergic receptors in the blood vessels of the nasal mucosa. By stimulating these receptors, vasoconstriction (narrowing of blood vessels) occurs. This reduces swelling of the mucous membrane, clearing the airways in the nose.

  Dosage: The usual dosage is 60 mg per dose, maximum 180 mg per day; do not use in case of high blood pressure or heart conditions.
• +Sertraline1 bronop voorschrift — vraag je arts
  About the substance

  Sertraline is a selective serotonin reuptake inhibitor (SSRI) that blocks the neuronal reuptake of serotonin, thereby increasing the serotonin concentration in the synaptic cleft.

  Dosage: Depression and OCD: start with 50 mg/day. Panic disorder, PTSD, and social anxiety disorder: start with 25 mg/day, increase to 50 mg/day after one week.
• +Doxorubicin1 bronop voorschrift — vraag je arts
  About the substance

  Cytotoxic anthracycline antibiotic that works via DNA intercalation between base pairs, leading to the blockage of DNA, RNA, and protein synthesis and the generation of reactive oxygen species.

  Dosage: Breast/ovarian cancer: 50 mg/m² intravenously every 4 weeks. Multiple myeloma: 30 mg/m² on day 4 of a 3-week cycle.
• +Atropine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Atropine is a competitive, reversible antagonist of muscarinic receptors (class: belladonna alkaloids). It blocks the effects of acetylcholine on postganglionic nerve endings in exocrine glands, smooth muscles, the heart muscle, and the central nervous system.

  Dosage: Premedication adults: 0.3-0.6 mg IV (or IM 30-60 min before surgery). Pediatric: 0.01-0.02 mg/kg (max. 0.6 mg). Combination with neostigmine adults: 0.6-1.2 mg IV; pediatric: 0.02 mg/kg IV.
• +Fluconazole1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  An azole antifungal agent that inhibits the synthesis of ergosterol in the fungal cell membrane by interacting with the enzyme cytochrome P450, leading to membrane damage and cell death.

  Dosage: Tablet or suspension, usually taken once daily, with or without food; the duration of treatment and dosage (sometimes a double starting dose) depend on the indication and response.
• +Aldesleukin1 bronop voorschrift — vraag je arts
  About the substance

  Recombinant interleukin-2 (IL-2) analog that stimulates the proliferation and activation of T-lymphocytes and natural killer cells to enhance the immune response against tumor cells.
• +Hyoscyamine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  A tropane alkaloid and antimuscarinic substance that acts as a competitive antagonist of acetylcholine at muscarinic receptors.

  Dosage: Tablets/liquid: 3-4 times per day. Extended-release capsules: 2 times per day (do not chew or crush). Antacids should be used 1 hour before or 2 hours after intake.
• +Paroxetine1 bronop voorschrift — vraag je arts
  About the substance

  Paroxetine is a selective serotonin reuptake inhibitor (SSRI) that blocks the reuptake of serotonin in brain neurons, thereby increasing the serotonin concentration in the synaptic cleft.

  Dosage: Starting dose 20 mg per day, potentially increased gradually in steps of 10 mg up to a maximum of 50 mg per day.
• +Fluoxetine1 bronop voorschrift — vraag je arts
  About the substance

  Fluoxetine is a selective serotonin reuptake inhibitor (SSRI). It blocks the reuptake of serotonin in the synaptic cleft, thereby increasing the serotonin concentration in the central nervous system.

  Dosage: Adults: 20 mg per day, which can be gradually increased to a maximum of 60 mg per day.
• +Thalidomide1 bronop voorschrift — vraag je arts
  About the substance

  Thalidomide is an immunomodulatory and anti-inflammatory agent that works by suppressing tumor necrosis factor-alpha (TNF-α) and modulating cytokine activity and angiogenesis.

  Dosage: 200 mg daily, taken orally, preferably at bedtime and at least 1 hour after the evening meal.
• +Clonidine1 bronop voorschrift — vraag je arts
  About the substance

  Clonidine is an imidazole derivative and centrally acting alpha-2-adrenergic agonist. By stimulating alpha-2 receptors in the medulla oblongata, sympathetic outflow is inhibited, leading to a reduction in peripheral resistance and heart rate.

  Dosage: Starting dose for hypertension: 75-150 micrograms twice daily. The dose can be increased in steps up to a maximum of 600 micrograms daily.
• +Epinephrine1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Epinephrine is a sympathomimetic that acts as an agonist on both alpha- and beta-adrenergic receptors, leading to powerful cardiovascular stimulation and bronchodilation.

  Dosage: For anaphylaxis: intramuscular injection into the outer thigh, immediately at the first signs of a severe reaction.
• +Ceftriaxone1 bronop voorschrift — vraag je arts
  About the substance

  Third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and bacterial death.

  Dosage: Adults and children ≥ 50 kg: 1-2 g once daily (in severe cases up to 2 g per day, possibly divided into 2 doses).
• +Cortisone1 bronop voorschrift — vraag je arts
  About the substance

  Natural glucocorticoid that is converted in the liver to the active metabolite hydrocortisone; acts as an anti-inflammatory and replacement therapy.
• +Methotrexate1 bronop voorschrift — vraag je arts
  About the substance

  Folic acid antagonist and cytostatic that inhibits the conversion of folic acid to tetrahydrofolic acid through competitive inhibition of dihydrofolate reductase, thereby blocking DNA synthesis and cell division in rapidly dividing tissues.

  Dosage: Individually determined, often based on body surface area (m²) or body weight; for rheumatoid arthritis or psoriasis, a weekly schedule is generally used.
• +Triamcinolone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Triamcinolone is a synthetic corticosteroid that exerts anti-inflammatory and immunosuppressive effects by binding to glucocorticoid receptors, leading to modulation of gene expression and suppression of the immune response.

  Dosage: For inhalation: 3 to 4 times daily at regular intervals. For injections (10-40 mg/ml) and dermatological applications, the dosage varies significantly depending on the indication and form of administration.
• +Ciprofloxacin1 bronop voorschrift — vraag je arts
  About the substance

  Ciprofloxacin is a bactericidal fluoroquinolone that inhibits bacterial DNA replication, transcription, and repair by inhibiting the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV.

  Dosage: The dosage depends on the indication, severity, kidney function, and weight; intravenous administration is usually via slow infusion over 60 minutes, every 8 to 12 hours.
• +Methylprednisolone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Methylprednisolone is a potent synthetic glucocorticoid that works by binding to intracellular receptors, leading to modulation of gene expression with strong immunosuppressive and anti-inflammatory effects.

  Dosage: Patient-dependent; the lowest possible dose should be used. Parenteral (as Na-succinate): starting dose 10–500 mg per day, depending on the indication.
• +Dexamethasone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Dexamethasone is a potent synthetic corticosteroid that works by binding to glucocorticoid receptors, leading to a strong anti-inflammatory and immunosuppressive response.
• +Prednisolone1 bronniet vrij verkrijgbaar — vraag je arts
  About the substance

  Glucocorticoid with anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive properties, acting by binding to glucocorticoid receptors.

  Dosage: Use eye drops or eye ointment strictly according to the prescription label; shake suspensions before use and avoid contact of the dropper with the eye.

Bron: dis-treat master (BCFI/itreat · EMA · SIDER · FAERS-frequentie). Geen diagnose — dit vervangt geen consult.